HNF4A

Gene Symbol HNF4A
Entrez Gene 3172
Alt Symbol FRTS4, HNF4, HNF4a7, HNF4a8, HNF4a9, HNF4alpha, MODY, MODY1, NR2A1, NR2A21, TCF, TCF14
Species Human
Gene Type protein-coding
Description hepatocyte nuclear factor 4, alpha
Other Description HNF4alpha10/11/12|TCF-14|hepatic nuclear factor 4 alpha|hepatocyte nuclear factor 4-alpha|nuclear receptor subfamily 2 group A member 1|transcription factor 14|transcription factor HNF-4
Swissprots Q9NQH0 Q6B4V6 Q14540 P41235 A5JW41 Q92655 O00723 B2RPP8 Q6B4V5 Q6B4V7 Q92654 Q92653 Q5QPB8 Q99864 O00659
Accessions AAB48082 AAB48083 AAM34296 ABQ52204 EAW75921 EAW75922 EAW75923 EAW75924 EAW75925 P41235 AB307703 BAH02294 AK096973 AW134564 AW935533 AY680696 AAT91237 AY680697 AAT91238 AY680698 AAT91239 BC137539 AAI37540 BC137540 AAI37541 BP274413 CB163637 FJ608822 ACM50922 HQ692860 ADZ17371 HQ692868 ADZ17379 HQ692869 ADZ17380 X76930 CAA54248 X87870 CAA61133 X87871 CAA61134 X87872 CAA61135 Z49825 CAA89989 XM_005260407 XP_005260464 XM_011528797 XP_011527099 XM_011528798 XP_011527100 NM_000457 NP_000448 NM_001030003 NP_001025174 NM_001030004 NP_001025175 NM_001258355 NP_001245284 NM_001287182 NP_001274111 NM_001287183 NP_001274112 NM_001287184 NP_001274113 NM_175914 NP_787110 NM_178849 NP_849180 NM_178850 NP_849181
Function Transcriptionally controlled transcription factor. Binds to DNA sites required for the transcription of alpha 1- antitrypsin, apolipoprotein CIII, transthyretin genes and HNF1- alpha. May be essential for development of the liver, kidney and intestine.
Subcellular Location Nucleus.
Top Pathways Maturity onset diabetes of the young, AMPK signaling pathway

HNF4α (C11F12) Rabbit mAb - 3113 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone C11F12
Western blot analysis of extract from HepG2 cells using HNF4α (C11F12) Rabbit mAb.

HNF4α (G162) Antibody - 3117 from Cell Signaling Technology

Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from HepG2 cells, using HNF4α (G162) Antibody.

HNF4α (E410) Antibody - 3105 from Cell Signaling Technology

Host Rabbit
Clonality Polyclonal

HNF-4α (H-1) - sc-374229 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
HNF-4α (H-1): sc-374229. Western blot analysis of HNF-4α expression in SW480 whole cell lysate.

HNF-4α (C-19) - sc-6556 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HNF-4α (C-19): sc-6556. Western blot analysis of HNF-4α expression in Hep G2 whole cell lysate.

HNF-4α (H-171) - sc-8987 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
HNF-4α (H-171): sc-8987. Immunofluorescence staining of methanol-fixed Hep G2 cells showing nuclear localization.

HNF-4α (Q-15) - sc-101059 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
HNF-4α (Q-15): sc-101059. Immunofluorescence staining of paraformaldehyde-fixed HeLa cells showing nuclear localization.

HNF-4α (S-20) - sc-6557 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HNF-4α (S-20): sc-6557. Immunofluorescence staining of methanol-fixed Hep G2 cells showing nuclear localization.

Anti-HNF-4-alpha + HNF-4-gamma antibody - ab64911 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-HNF-4-alpha + HNF-4-gamma antibody (ab64911) at 1/500 dilutionLane 1 : extracts from HeLa cellsLane 2 : extracts from HepG2 cellsLane 3 : extracts from 293 cellsLane 4 : extracts from 293 cells with immunising peptide at 10 µgLysates/proteins at 30 µg per lane.

Anti-HNF-4-alpha (phospho S304) antibody - ab194930 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-HNF-4-alpha (phospho S304) antibody (ab194930) at 1/500 dilutionLane 1 : HeLa cell extract untreatedLane 2 : HeLa cell extract treated with Anisomycin

Anti-HNF-4-alpha (phospho S313) antibody - ab78356 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-HNF-4-alpha (phospho S313) antibody (ab78356) at 1/500 dilutionLane 1 : Extracts from HUVEC cells, treated with EGF (200ng/ml, 30mins)Lane 2 : Extracts from HUVEC cells, treated with EGF (200ng/ml, 30mins) with immunising peptide at 10 µgLysates/proteins at 30 µg per lane.

Anti-HNF-4-alpha (phospho S313) antibody - ab195730 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-HNF-4-alpha (phospho S313) antibody (ab195730) at 1/500 dilutionLane 1 : EGF treated HuvEc whole cell lysate with antigen-specific peptideLane 2 : EGF treated HuvEc whole cell lysateLysates/proteins at 12.5 µg per lane.

Anti-HNF-4-alpha antibody - ab139420 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-HNF-4-alpha antibody (ab139420) at 1 µg/ml + Kidney (Human) Tissue Lysate - adult normal tissue at 25 µgSecondaryGoat Anti-Rabbit IgG H&L (HRP) (ab97051) at 1/10000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-HNF-4-alpha antibody - ab55223 from Abcam

Prices $384.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-HNF-4-alpha antibody - ab76649 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-HNF-4-alpha antibody (ab76649) at 1/50 dilution + NCI-H460 cell line lysates at 35 µg

Anti-HNF-4-alpha antibody - ab36175 from Abcam

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-HNF-4-alpha antibody (ab36175) at 0.1 µg/ml + HepG2 lysate (35µg protein in RIPA buffer).

Anti-HNF-4-alpha antibody - ab136861 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-HNF-4-alpha antibody (ab136861) at 1/500 dilution + HepG2 cell lysate at 30 µg

Anti-HNF-4-alpha antibody [EPR16786] - N-terminal - ab199431 from Abcam

Prices $347.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR16786
All lanes : Anti-HNF-4-alpha antibody [EPR16786] - N-terminal (ab199431) at 1/10000 dilutionLane 1 : Mouse liver lysateLane 2 : Rat liver lysateLane 3 : Human fetal liver lysateLane 4 : Human stomach lysateLysates/proteins at 10 µg per lane.SecondaryAnti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at 1/1000 dilution

Anti-HNF-4-alpha antibody [EPR16885] - ab181604 from Abcam

Prices $347.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR16885
Anti-HNF-4-alpha antibody [EPR16885] (ab181604) at 1/1000 dilution + Full length mouse HNF-4-gamma recombinant protein at 10 µgSecondaryGoat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/1000 dilution

Anti-HNF-4-alpha antibody [EPR16885-99] - ab201460 from Abcam

Prices $347.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR16885-99
Anti-HNF-4-alpha antibody [EPR16885-99] (ab201460) at 1/1000 dilution + Full length mouse HNF-4-gamma recombinant protein at 10 µgSecondaryGoat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/1000 dilution

Anti-HNF-4-alpha antibody [EPR3648] - ab92378 from Abcam

Prices $394.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3648
All lanes : Anti-HNF-4-alpha antibody [EPR3648] (ab92378) at 1/1000 dilution (unpurified)Lane 1 : HepG2 cell lysateLane 2 : A549 cell lysateLane 3 : SW480 cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP-conjugated goat anti-rabbit IgG at 1/2000 dilution

Anti-HNF-4-alpha antibody [EPR3649] - ab133343 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3649
All lanes : Anti-HNF-4-alpha antibody [EPR3649] (ab133343) at 1/1000 dilutionLane 1 : HepG2 cell lysateLane 2 : Human fetal liver lysateLysates/proteins at 10 µg per lane.SecondaryGoat Anti-rabbit HRP at 1/2000 dilution

Anti-HNF-4-alpha antibody [MM0754-17F66] - ab201592 from Abcam

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MM0754-17F66

Anti-HNF4A / HNF4 Antibody (aa164-474) - LS-C344069 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
HNF-4-alpha antibody IHC-paraffin: Human Intestinal Cancer Tissue.

Anti-HNF4A / HNF4 Antibody (Gly162) - LS-C36651 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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