| Gene Symbol | CDK20 |
|---|---|
| Entrez Gene | 23552 |
| Alt Symbol | CCRK, CDCH, P42, PNQALRE |
| Species | Human |
| Gene Type | protein-coding |
| Description | cyclin-dependent kinase 20 |
| Other Description | CAK-kinase p42|CDK-activating kinase p42|cell cycle-related kinase|cell division protein kinase 20|cyclin-dependent protein kinase H|cyclin-kinase-activating kinase p42 |
| Swissprots | Q5VYW1 Q5EDC4 B4DQX1 Q8IZL9 O95137 A2A390 Q9BUF4 A2A389 |
| Accessions | AAN28684 CAF86933 EAW62743 EAW62744 EAW62745 EAW62746 EAW62747 EAW62748 EAW62749 Q8IZL9 AF035013 AAC98920 AF113130 AAF43778 AI479563 AK075325 BAG52110 AK226135 AK291713 BAF84402 AK294193 BAG57509 AK296328 BAG59019 AK298993 BAG61083 AY904367 AAW82349 BC002655 AAH02655 BF966262 BI757318 BM982394 BX647489 CB992644 DB469301 XM_011518425 XP_011516727 XM_011518426 XP_011516728 XM_011518427 XP_011516729 XM_011518428 XP_011516730 XM_011518429 XP_011516731 XM_011518430 XP_011516732 XM_011518431 XP_011516733 XM_011518432 XP_011516734 XM_011518433 XP_011516735 XM_011518434 XP_011516736 XM_011518435 XP_011516737 XM_011518436 XP_011516738 NM_001039803 NP_001034892 NM_001170639 NP_001164110 NM_001170640 NP_001164111 NM_012119 NP_036251 NM_178432 NP_848519 |
| Function | Required for high-level Shh responses in the developing neural tube. Together with TBC1D32, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to SHH signaling (By similarity). Involved in cell growth. Activates CDK2, a kinase involved in the control of the cell cycle, by phosphorylating residue 'Thr-160'. {ECO:0000250, ECO:0000269|PubMed:14597612}. |
| Subcellular Location | Nucleus {ECO:0000269|PubMed:14597612}. Cytoplasm {ECO:0000250}. Cell projection, cilium {ECO:0000250}. |