Gene Symbol | PPM1F |
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Entrez Gene | 9647 |
Alt Symbol | CAMKP, CaMKPase, FEM-2, POPX2, hFEM-2 |
Species | Human |
Gene Type | protein-coding |
Description | protein phosphatase, Mg2+/Mn2+ dependent, 1F |
Other Description | Ca(2+)/calmodulin-dependent protein kinase phosphatase|CaM-kinase phosphatase|PP2C phosphatase|partner of PIX 2|protein fem-2 homolog|protein phosphatase 1F|protein phosphatase 1F (PP2C domain containing) |
Swissprots | Q96PM2 A8K6G3 P49593 B7Z2C3 |
Accessions | BAA19990 EAW59483 EAW59484 EAW59485 P49593 AF305840 AAL15579 AF520615 AAM76059 AK126377 BAG54318 AK291628 BAF84317 AK294557 BAH11809 AU127806 BC071989 AAH71989 BC105599 AAI05600 CA425300 D13640 BAA02803 DA311634 EU831437 ACE87124 EU831529 ACE86448 N34773 XM_011530556 XP_011528858 NM_014634 NP_055449 |
Function | Dephosphorylates and concomitantly deactivates CaM- kinase II activated upon autophosphorylation, and CaM-kinases IV and I activated upon phosphorylation by CaM-kinase kinase. Promotes apoptosis. |
POPX2 CRISPR/Cas9 KO Plasmid (h) - sc-406536 from Santa Cruz Biotechnology
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POPX2 HDR Plasmid (h) - sc-406536-HDR from Santa Cruz Biotechnology
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POPX2 Double Nickase Plasmid (h) - sc-406536-NIC from Santa Cruz Biotechnology
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POPX2 Double Nickase Plasmid (h2) - sc-406536-NIC-2 from Santa Cruz Biotechnology
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POPX2 CRISPR Activation Plasmid (h) - sc-406536-ACT from Santa Cruz Biotechnology
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POPX2 CRISPR Activation Plasmid (h2) - sc-406536-ACT-2 from Santa Cruz Biotechnology
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POPX2 Lentiviral Activation Particles (h) - sc-406536-LAC from Santa Cruz Biotechnology
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POPX2 Lentiviral Activation Particles (h2) - sc-406536-LAC-2 from Santa Cruz Biotechnology
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POPX2 siRNA (h) - sc-62844 from Santa Cruz Biotechnology
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POPX2 shRNA Plasmid (h) - sc-62844-SH from Santa Cruz Biotechnology
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POPX2 shRNA (h) Lentiviral Particles - sc-62844-V from Santa Cruz Biotechnology
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Protein phosphatase 1F RNAi - H00009647-R02 from Novus Biologicals
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MISSION® Human Phosphatase - SIHP0487 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0489 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0488 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17244 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17244 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR14117 from Sigma-Aldrich
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PPM1F siRNA (Human) - CRH6424 from Cohesion Biosciences
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shRNA set against Human PPM1F (NM_014634.3) - SHH380832 from Creative biogene
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POPX2 CRISPR/Cas9 KO Plasmid (h2) - sc-406536-KO-2 from Santa Cruz Biotechnology
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POPX2 HDR Plasmid (h2) - sc-406536-HDR-2 from Santa Cruz Biotechnology
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Human PPM1F siRNA - orb266926 from Biorbyt
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PPM1F shRNA Plasmid (Human) - CHH6424 from Cohesion Biosciences
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PPM1F miRNA 3'UTR clone - MiUTR4H-TG06939 from Creative biogene
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