Gene Symbol | IL18BP |
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Entrez Gene | 10068 |
Alt Symbol | IL18BPa |
Species | Human |
Gene Type | protein-coding |
Description | interleukin 18 binding protein |
Other Description | IL-18BP|MC51L-53L-54L homolog gene product|interleukin-18-binding protein|tadekinig-alfa |
Swissprots | O95993 B3KUZ0 O96027 B7WPK4 Q9UBR7 Q9NZA9 O95998 |
Accessions | AAD17187 AAD17188 AAD17189 AAD41053 EAW74812 EAW74813 EAW74814 EAW74815 EAW74816 EAW74817 EAW74818 EAW74819 EAW74820 O95998 AB019504 BAA76374 AF086560 AF110799 AAD17190 AF110800 AAD17191 AF110801 AAD17192 AF122906 AAD41051 AF215907 AAF31697 AK098255 BAG53602 AL698586 AW295729 BC044215 AAH44215 BF934342 BM819966 BX357194 CB154498 HQ448621 ADQ33099 XM_006718406 XP_006718469 XM_006718408 XP_006718471 XM_006718410 XP_006718473 XM_011544716 XP_011543018 XM_011544717 XP_011543019 NM_001039659 NP_001034748 NM_001039660 NP_001034749 NM_001145055 NP_001138527 NM_001145057 NP_001138529 NM_005699 NP_005690 NM_173042 NP_766630 NM_173044 NP_766632 NM_173043 |
Function | Isoform A binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokine response. {ECO:0000269|PubMed:10023777, ECO:0000269|PubMed:10655506}. |
Subcellular Location | Secreted {ECO:0000305}. |
Tissue Specificity | Strongly expressed in heart, lung, placenta and spleen. {ECO:0000269|PubMed:10023777, ECO:0000269|PubMed:10094485}. |
IL-18BP CRISPR/Cas9 KO Plasmid (h) - sc-403516 from Santa Cruz Biotechnology
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IL-18BP HDR Plasmid (h) - sc-403516-HDR from Santa Cruz Biotechnology
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IL-18BP Double Nickase Plasmid (h) - sc-403516-NIC from Santa Cruz Biotechnology
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IL-18BP Double Nickase Plasmid (h2) - sc-403516-NIC-2 from Santa Cruz Biotechnology
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IL-18BP CRISPR Activation Plasmid (h) - sc-403516-ACT from Santa Cruz Biotechnology
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IL-18BP CRISPR Activation Plasmid (h2) - sc-403516-ACT-2 from Santa Cruz Biotechnology
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IL-18BP Lentiviral Activation Particles (h) - sc-403516-LAC from Santa Cruz Biotechnology
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IL-18BP Lentiviral Activation Particles (h2) - sc-403516-LAC-2 from Santa Cruz Biotechnology
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IL-18BP siRNA (h) - sc-105566 from Santa Cruz Biotechnology
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IL-18BP shRNA Plasmid (h) - sc-105566-SH from Santa Cruz Biotechnology
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IL-18BP shRNA (h) Lentiviral Particles - sc-105566-V from Santa Cruz Biotechnology
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IL-18 BPa/IL18BP RNAi - H00010068-R02 from Novus Biologicals
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IL-18 BPa/IL18BP RNAi - H00010068-R03 from Novus Biologicals
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MISSION® esiRNA - EHU139701 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10586 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10586 from Sigma-Aldrich
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IL18BP siRNA (Human) - CRH6782 from Cohesion Biosciences
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IL-18 BPa/IL18BP RNAi - H00010068-R01 from Novus Biologicals
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IL18BP - MBS8227602 from MyBioSource
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shRNA set against Human IL18BP(NM_001039659.1) - SHL172026 from Creative biogene
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Human IL18BP siRNA - orb267284 from Biorbyt
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IL18BP shRNA Plasmid (Human) - CHH6782 from Cohesion Biosciences
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IL18BP miRNA 3'UTR clone - MiUTR1H-04885 from Creative biogene
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IL18BP miRNA 3'UTR clone - MiUTR3H-06561 from Creative biogene
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IL18BP miRNA 3'UTR clone - MiUTR3H-06562 from Creative biogene
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