Gene Symbol | TPT1 |
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Entrez Gene | 7178 |
Alt Symbol | HRF, TCTP, p02, p23 |
Species | Human |
Gene Type | protein-coding |
Description | tumor protein, translationally-controlled 1 |
Other Description | fortilin|histamine-releasing factor|translationally-controlled tumor protein |
Swissprots | Q7Z4J4 B2R7E5 P13693 Q9UC70 Q8TBK7 Q6YLS2 Q96EE2 |
Accessions | CAB87812 CAD34870 EAX08731 EAX08732 EAX08733 EAX08734 EAX08735 P13693 AF072098 AAD48084 AK130847 AK296587 BAG59206 AK296952 BAG59498 AK312951 BAG35792 AY117678 AAM51565 AY334563 AAQ01550 BC003352 AAH03352 BC007842 BC012431 AAH12431 BC022436 AAH22436 BC040008 AAH40008 BC052333 AAH52333 BP215975 CR457036 CAG33317 D28408 BAA05774 JF432827 ADZ16044 L13806 X16064 CAA34200 X64899 NM_001286272 NP_001273201 NM_001286273 NP_001273202 NM_003295 NP_003286 |
Function | Involved in calcium binding and microtubule stabilization. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:9059837}. |
Tissue Specificity | Found in several healthy and tumoral cells including erythrocytes, hepatocytes, macrophages, platelets, keratinocytes, erythroleukemia cells, gliomas, melanomas, hepatoblastomas, and lymphomas. It cannot be detected in kidney and renal cell carcinoma (RCC). Expressed in placenta and prostate. {ECO:0000269|PubMed:9059837}. |
HRF CRISPR/Cas9 KO Plasmid (h) - sc-402606 from Santa Cruz Biotechnology
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HRF HDR Plasmid (h) - sc-402606-HDR from Santa Cruz Biotechnology
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HRF Double Nickase Plasmid (h) - sc-402606-NIC from Santa Cruz Biotechnology
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HRF Double Nickase Plasmid (h2) - sc-402606-NIC-2 from Santa Cruz Biotechnology
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HRF CRISPR Activation Plasmid (h) - sc-402606-ACT from Santa Cruz Biotechnology
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HRF CRISPR Activation Plasmid (h2) - sc-402606-ACT-2 from Santa Cruz Biotechnology
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HRF Lentiviral Activation Particles (h) - sc-402606-LAC from Santa Cruz Biotechnology
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HRF Lentiviral Activation Particles (h2) - sc-402606-LAC-2 from Santa Cruz Biotechnology
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HRF siRNA (h) - sc-40675 from Santa Cruz Biotechnology
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HRF shRNA Plasmid (h) - sc-40675-SH from Santa Cruz Biotechnology
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HRF shRNA (h) Lentiviral Particles - sc-40675-V from Santa Cruz Biotechnology
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TPT1/TCTP RNAi - H00007178-R01 from Novus Biologicals
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MISSION® esiRNA - EHU111621 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21892 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21892 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02187 from Sigma-Aldrich
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TPT1 siRNA (Human) - CRH4928 from Cohesion Biosciences
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TCTP - MBS826838 from MyBioSource
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TPT1 - MBS8212802 from MyBioSource
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shRNA set against Human TPT1 (NM_003295.2) - SHH433584 from Creative biogene
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shRNA set against Human TPT1(NM_003295.2) - SHL090486 from Creative biogene
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TPT1 shRNA Plasmid (Human) - CHH4928 from Cohesion Biosciences
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TPT1 miRNA 3'UTR clone - MiUTR1H-10686 from Creative biogene
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