Gene Symbol |
KRTAP17-1
|
Entrez Gene |
83902
|
Alt Symbol |
KAP17.1, KRTAP16.1, KRTAP17.1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
keratin associated protein 17-1
|
Other Description |
keratin associated protein 16.1|keratin-associated protein 16.1|keratin-associated protein 17-1
|
Swissprots |
Q9BYP8
|
Accessions |
EAW60726 Q9BYP8 AJ406952 CAC27591 BC069078 AAH69078 BC069297 AAH69297 BC146276 AAI46277 BC146560 AAI46561 NM_031964 NP_114170
|
Function |
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins.
|