Gene Symbol | SLC19A2 |
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Entrez Gene | 10560 |
Alt Symbol | TC1, THMD1, THT1, THTR1, TRMA |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 19 (thiamine transporter), member 2 |
Other Description | high affinity thiamine transporter|reduced folate carrier protein (RFC) like|solute carrier family 19 member 2|thTr-1|thiamine transporter 1 |
Swissprots | Q9UKJ2 Q8WV87 B4E1X4 B2R9H0 Q9UN31 Q9UN43 O60779 Q9UBL7 |
Accessions | AAD51280 AAD51283 AAD54242 AAP37965 ABY51619 ADP24156 AFO38177 CAB50771 EAW90843 EAW90844 EAW90845 EAW90846 EAW90847 O60779 AB209540 BAD92777 AF135488 AAD45985 AF153330 AAD43534 AF160812 AAF15129 AF272359 AAK54468 AJ237724 CAB50770 AK304021 BAG64936 AK313779 BAG36517 AK316465 BAH14836 BC018514 AAH18514 BU608154 XM_011509076 XP_011507378 XM_011509077 XP_011507379 NM_006996 NP_008927 |
Function | High-affinity transporter for the intake of thiamine. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Ubiquitous; most abundant in skeletal and cardiac muscle. Medium expression in placenta, heart, liver and kidney, low in lung. |
Top Pathways | Vitamin digestion and absorption |
THTR1 CRISPR/Cas9 KO Plasmid (h) - sc-404528 from Santa Cruz Biotechnology
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THTR1 HDR Plasmid (h) - sc-404528-HDR from Santa Cruz Biotechnology
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THTR1 Double Nickase Plasmid (h) - sc-404528-NIC from Santa Cruz Biotechnology
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THTR1 Double Nickase Plasmid (h2) - sc-404528-NIC-2 from Santa Cruz Biotechnology
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THTR1 CRISPR Activation Plasmid (h) - sc-404528-ACT from Santa Cruz Biotechnology
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THTR1 CRISPR Activation Plasmid (h2) - sc-404528-ACT-2 from Santa Cruz Biotechnology
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THTR1 Lentiviral Activation Particles (h) - sc-404528-LAC from Santa Cruz Biotechnology
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THTR1 Lentiviral Activation Particles (h2) - sc-404528-LAC-2 from Santa Cruz Biotechnology
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THTR1 siRNA (h) - sc-106612 from Santa Cruz Biotechnology
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THTR1 shRNA Plasmid (h) - sc-106612-SH from Santa Cruz Biotechnology
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THTR1 shRNA (h) Lentiviral Particles - sc-106612-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN2363 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2363 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10773 from Sigma-Aldrich
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SLC19A2 siRNA (Human) - CRH7181 from Cohesion Biosciences
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SLC19A2 RNAi - H00010560-R01 from Novus Biologicals
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SLC19A2 - MBS8222861 from MyBioSource
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shRNA set against Human SLC19A2 (NM_006996.2) - SHH408872 from Creative biogene
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SLC19A2 shRNA Plasmid (Human) - CHH7181 from Cohesion Biosciences
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SLC19A2 miRNA 3'UTR clone - MiUTR3H-06402 from Creative biogene
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