| Gene Symbol |
RAB30
|
| Entrez Gene |
27314
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
RAB30, member RAS oncogene family
|
| Other Description |
ras-related protein Rab-30
|
| Swissprots |
Q6MZH2 Q96CI8 Q15771 Q6FGK1
|
| Accessions |
EAW75078 EAW75079 EAW75080 EAW75081 Q15771 AF498956 AAM21104 AK092185 AK291376 BAF84065 AK310082 AK312323 BAG35245 BC014213 AAH14213 BC032890 BP310715 BP336371 BX641138 CAE46061 CR542106 CAG46903 DB151524 DQ892631 ABM83557 DQ895871 ABM86797 EU176714 ABW03515 U57092 AAC50774 NM_001286059 NP_001272988 NM_001286060 NP_001272989 NM_001286061 NP_001272990 NM_014488 NP_055303
|
| Function |
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). Required for maintaining the structural integrity of the Golgi apparatus, possibly by mediating interactions with cytoplasmic scaffolding proteins. {ECO:0000250, ECO:0000269|PubMed:22188167}.
|
| Subcellular Location |
Membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Golgi apparatus, trans-Golgi network {ECO:0000269|PubMed:22188167}. Cytoplasm {ECO:0000269|PubMed:22188167}. Golgi apparatus {ECO:0000269|PubMed:22188167}.
|