Gene Symbol | KLRC2 |
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Entrez Gene | 3822 |
Alt Symbol | CD159c, NKG2-C, NKG2C |
Species | Human |
Gene Type | protein-coding |
Description | killer cell lectin-like receptor subfamily C, member 2 |
Other Description | CD159 antigen-like family member C|NK cell receptor C|NKG2-C type II integral membrane protein|NKG2-C-activating NK receptor |
Swissprots | Q52M74 P26717 Q9NR42 O43802 |
Accessions | AAG26338 CAA04922 P26717 AF260134 AAF86972 AK295525 BAG58438 BC093644 AAH93644 BC106069 AAI06070 BC112039 AAI12040 X54869 CAA38651 Y13055 CAA73498 NM_002260 NP_002251 |
Function | Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. |
Subcellular Location | Membrane; Single-pass type II membrane protein. |
Tissue Specificity | Natural killer cells. |
Top Pathways | Natural killer cell mediated cytotoxicity, Antigen processing and presentation |
NKG2-C CRISPR/Cas9 KO Plasmid (h) - sc-408580 from Santa Cruz Biotechnology
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NKG2-C HDR Plasmid (h) - sc-408580-HDR from Santa Cruz Biotechnology
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NKG2-C Double Nickase Plasmid (h) - sc-408580-NIC from Santa Cruz Biotechnology
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NKG2-C Double Nickase Plasmid (h2) - sc-408580-NIC-2 from Santa Cruz Biotechnology
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NKG2-C CRISPR Activation Plasmid (h) - sc-408580-ACT from Santa Cruz Biotechnology
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NKG2-C CRISPR Activation Plasmid (h2) - sc-408580-ACT-2 from Santa Cruz Biotechnology
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NKG2-C Lentiviral Activation Particles (h) - sc-408580-LAC from Santa Cruz Biotechnology
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NKG2-C Lentiviral Activation Particles (h2) - sc-408580-LAC-2 from Santa Cruz Biotechnology
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NKG2-C siRNA (h) - sc-72387 from Santa Cruz Biotechnology
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NKG2-C shRNA Plasmid (h) - sc-72387-SH from Santa Cruz Biotechnology
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NKG2-C shRNA (h) Lentiviral Particles - sc-72387-V from Santa Cruz Biotechnology
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NKG2C/CD159c/KLRC2 RNAi - H00003822-R02 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN11322 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11322 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03923 from Sigma-Aldrich
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KLRC2 siRNA (Human) - CRH2590 from Cohesion Biosciences
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shRNA set against Human KLRC2(NM_002260.3) - SHL203634 from Creative biogene
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Human KLRC2 siRNA - orb263092 from Biorbyt
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KLRC2 shRNA Plasmid (Human) - CHH2590 from Cohesion Biosciences
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KLRC2 miRNA 3'UTR clone - MiUTR1H-05412 from Creative biogene
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