Gene Symbol | CLN8 |
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Entrez Gene | 2055 |
Alt Symbol | C8orf61, EPMR |
Species | Human |
Gene Type | protein-coding |
Description | ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) |
Other Description | protein CLN8 |
Swissprots | Q9UBY8 Q96I95 Q86U71 |
Accessions | CAI93436 EAW51477 EAW51478 EAW51479 Q9UBY8 AF123757 AAF13115 AF123758 AAF13116 AF123759 AAF13117 AF123760 AAF13118 AF123761 AAF13119 AK096736 BAC04854 AK312486 AW296697 BC007725 AAH07725 BC136825 AAI36826 BC141858 BT007049 AAP35698 DA193710 XM_005266021 XP_005266078 XM_005266022 XP_005266079 XM_005266023 XP_005266080 XM_006725753 XP_006725816 XM_006725754 XP_006725817 XM_006725755 XP_006725818 XM_011534745 XP_011533047 XM_011534746 XP_011533048 XM_011534747 XP_011533049 XM_011547744 XP_011546046 XM_011547745 XP_011546047 XM_011547746 XP_011546048 NM_018941 NP_061764 NM_001034061 |
Function | Could play a role in cell proliferation during neuronal differentiation and in protection against cell death. {ECO:0000269|PubMed:19431184}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:10861296}; Multi-pass membrane protein {ECO:0000269|PubMed:10861296}. Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000269|PubMed:10861296}; Multi-pass membrane protein {ECO:0000269|PubMed:10861296}. |
CLN8 CRISPR/Cas9 KO Plasmid (h) - sc-410772 from Santa Cruz Biotechnology
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CLN8 HDR Plasmid (h) - sc-410772-HDR from Santa Cruz Biotechnology
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CLN8 Double Nickase Plasmid (h) - sc-410772-NIC from Santa Cruz Biotechnology
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CLN8 Double Nickase Plasmid (h2) - sc-410772-NIC-2 from Santa Cruz Biotechnology
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CLN8 CRISPR Activation Plasmid (h) - sc-410772-ACT from Santa Cruz Biotechnology
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CLN8 CRISPR Activation Plasmid (h2) - sc-410772-ACT-2 from Santa Cruz Biotechnology
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CLN8 Lentiviral Activation Particles (h) - sc-410772-LAC from Santa Cruz Biotechnology
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CLN8 Lentiviral Activation Particles (h2) - sc-410772-LAC-2 from Santa Cruz Biotechnology
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CLN8 siRNA (h) - sc-60411 from Santa Cruz Biotechnology
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CLN8 shRNA Plasmid (h) - sc-60411-SH from Santa Cruz Biotechnology
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CLN8 shRNA (h) Lentiviral Particles - sc-60411-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU020581 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6250 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6250 from Sigma-Aldrich
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CLN8 siRNA (Human) - CRH1432 from Cohesion Biosciences
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CLN8 - MBS8200212 from MyBioSource
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shRNA set against Human CLN8 (NM_018941.3) - SHH265517 from Creative biogene
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shRNA set against Human CLN8(NM_018941.3) - SHG183565 from Creative biogene
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Human CLN8 siRNA - orb261934 from Biorbyt
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CLN8 shRNA Plasmid (Human) - CHH1432 from Cohesion Biosciences
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CLN8 miRNA 3'UTR clone - MiUTR1H-02233 from Creative biogene
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