Gene Symbol | Tpk1 |
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Entrez Gene | 29807 |
Alt Symbol | - |
Species | Mouse |
Gene Type | protein-coding |
Description | thiamine pyrophosphokinase |
Other Description | mTPK1|thiamin pyrophosphokinase 1|thiamine pyrophosphokinase 1 |
Swissprots | Q8CAB5 Q3UWB5 Q8R1Q6 Q8CEE8 Q9R0M5 |
Accessions | EDL13442 EDL13443 EDL13444 EDL13445 Q9R0M5 AB027568 BAA87040 AK028431 BAC25948 AK033192 AK034521 AK035044 BAC28923 AK039131 BAC30248 AK052225 AK087844 AK136486 BAE23001 AK195079 BC015246 AAH15246 BC023354 AAH23354 XM_006506218 XP_006506281 XM_006506219 XP_006506282 XM_006506220 XP_006506283 NM_013861 NP_038889 |
Function | Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate. Can also catalyze the phosphorylation of pyrithiamine to pyrithiamine pyrophosphate. {ECO:0000269|PubMed:10567383, ECO:0000269|PubMed:16365036}. |
Tissue Specificity | Detected in kidney and liver, and at lower levels in heart, brain and testis. {ECO:0000269|PubMed:10567383}. |
Top Pathways | Thiamine metabolism |
TPK1 CRISPR/Cas9 KO Plasmid (m) - sc-424344 from Santa Cruz Biotechnology
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TPK1 HDR Plasmid (m) - sc-424344-HDR from Santa Cruz Biotechnology
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TPK1 Double Nickase Plasmid (m) - sc-424344-NIC from Santa Cruz Biotechnology
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TPK1 Double Nickase Plasmid (m2) - sc-424344-NIC-2 from Santa Cruz Biotechnology
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TPK1 CRISPR Activation Plasmid (m) - sc-424344-ACT from Santa Cruz Biotechnology
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TPK1 CRISPR Activation Plasmid (m2) - sc-424344-ACT-2 from Santa Cruz Biotechnology
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TPK1 Lentiviral Activation Particles (m) - sc-424344-LAC from Santa Cruz Biotechnology
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TPK1 Lentiviral Activation Particles (m2) - sc-424344-LAC-2 from Santa Cruz Biotechnology
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TPK1 siRNA (m) - sc-154570 from Santa Cruz Biotechnology
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TPK1 shRNA Plasmid (m) - sc-154570-SH from Santa Cruz Biotechnology
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TPK1 shRNA (m) Lentiviral Particles - sc-154570-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU061171 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN43337 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND43337 from Sigma-Aldrich
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TPK1 siRNA (Mouse) - CRM5006 from Cohesion Biosciences
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TPK1 - MBS8201864 from MyBioSource
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shRNA set against Mouse TPK1 (NM_013861.3) - SHH433308 from Creative biogene
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shRNA set against Mouse Tpk1(NM_013861.3) - SHL089832 from Creative biogene
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Mouse TPK1 siRNA - orb284482 from Biorbyt
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TPK1 shRNA Plasmid (Mouse) - CHM5006 from Cohesion Biosciences
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TPK1 miRNA 3'UTR clone - MiUTR1M-12065 from Creative biogene
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