Gene Symbol | SRP54 |
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Entrez Gene | 6729 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | signal recognition particle 54kDa |
Other Description | signal recognition particle 54 kDa protein|signal recognition particle 54kD |
Swissprots | P13624 B2R759 P61011 B4DUW6 |
Accessions | CAA60132 P61011 AK293319 BAG56838 AK300824 BAG62478 AK312853 BAG35706 BC000652 AAH00652 BC003389 AAH03389 DA495064 JF432694 ADZ15911 U51920 AAC50994 XM_005268024 XP_005268081 XM_011537106 XP_011535408 XM_011537107 XP_011535409 NM_001146282 NP_001139754 NM_003136 NP_003127 |
Function | Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). |
Subcellular Location | Nucleus speckle {ECO:0000269|PubMed:14729963}. Cytoplasm {ECO:0000269|PubMed:14729963}. |
Top Pathways | Protein export |
SRP54 CRISPR/Cas9 KO Plasmid (h) - sc-403655 from Santa Cruz Biotechnology
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SRP54 HDR Plasmid (h) - sc-403655-HDR from Santa Cruz Biotechnology
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SRP54 Double Nickase Plasmid (h) - sc-403655-NIC from Santa Cruz Biotechnology
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SRP54 Double Nickase Plasmid (h2) - sc-403655-NIC-2 from Santa Cruz Biotechnology
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SRP54 CRISPR Activation Plasmid (h) - sc-403655-ACT from Santa Cruz Biotechnology
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SRP54 CRISPR Activation Plasmid (h2) - sc-403655-ACT-2 from Santa Cruz Biotechnology
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SRP54 Lentiviral Activation Particles (h) - sc-403655-LAC from Santa Cruz Biotechnology
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SRP54 Lentiviral Activation Particles (h2) - sc-403655-LAC-2 from Santa Cruz Biotechnology
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SRP54 siRNA (h) - sc-106810 from Santa Cruz Biotechnology
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SRP54 shRNA Plasmid (h) - sc-106810-SH from Santa Cruz Biotechnology
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SRP54 shRNA (h) Lentiviral Particles - sc-106810-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU008571 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20580 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20580 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03067 from Sigma-Aldrich
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SRP54 siRNA (Human) - CRH4596 from Cohesion Biosciences
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SRP54 RNAi - H00006729-R02 from Novus Biologicals
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SRP54 - MBS8213374 from MyBioSource
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shRNA set against Human SRP54 (NM_003136.3) - SHH417920 from Creative biogene
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SRP54 shRNA Plasmid (Human) - CHH4596 from Cohesion Biosciences
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SRP54 miRNA 3'UTR clone - MiUTR3H-07141 from Creative biogene
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SRP54 miRNA 3'UTR clone - MiUTR3H-07142 from Creative biogene
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