Gene Symbol | NHP6B |
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Entrez Gene | 852386 |
Alt Symbol | YBR090C-A |
Species | Yeast |
Gene Type | protein-coding |
Description | Nhp6bp |
Other Description | - |
Swissprots | P89501 P11633 D6VQ90 A2TBM2 P89500 |
Accessions | DAA07210 P11633 NM_001180058 NP_009647 |
Function | DNA-binding protein that induces severe bending of DNA. Required for DNA-binding by the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. Also augments the fidelity of transcription by RNA polymerase III independently of any role in the FACT complex. Required for transcriptional initiation fidelity of some but not all tRNA genes. Seems to be functionally redundant with NHP6A. {ECO:0000269|PubMed:11118215, ECO:0000269|PubMed:11239460, ECO:0000269|PubMed:11287614, ECO:0000269|PubMed:11432837, ECO:0000269|PubMed:12952948, ECO:0000269|PubMed:14585989, ECO:0000269|PubMed:16407207, ECO:0000269|PubMed:7721780, ECO:0000269|PubMed:8946917}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00267, ECO:0000269|PubMed:14562095}. Chromosome {ECO:0000269|PubMed:14562095}. |
Recombinant Saccharomyces cerevisiae Non-histone chromosomal protein 6B(NHP6B) - CSB-YP320890SVG CSB-EP320890SVG CSB-BP320890SVG CSB-MP320890SVG from Cusabio
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Non-histone chromosomal protein 6B (NHP6B), Recombinant Protein - MBS1186585 from MyBioSource
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