Gene Symbol | CCL7 |
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Entrez Gene | 6354 |
Alt Symbol | FIC, MARC, MCP-3, MCP3, NC28, SCYA6, SCYA7 |
Species | Human |
Gene Type | protein-coding |
Description | chemokine (C-C motif) ligand 7 |
Other Description | C-C motif chemokine 7|monocyte chemoattractant protein 3|monocyte chemotactic protein 3|small inducible cytokine A7 (monocyte chemotactic protein 3)|small-inducible cytokine A7 |
Swissprots | P80098 Q569J6 |
Accessions | CAB59723 EAW80210 P80098 AF043338 AAC03538 BC070240 BC092436 AAH92436 BC112258 AAI12259 BC112260 AAI12261 CD523198 HQ258695 ADR83446 X71087 CAA50405 NM_006273 NP_006264 |
Function | Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity. Also induces the release of gelatinase B. This protein can bind heparin. Binds to CCR1, CCR2 and CCR3. |
Subcellular Location | Secreted. |
Top Pathways | Cytokine-cytokine receptor interaction, Chemokine signaling pathway |
MCP-3 CRISPR/Cas9 KO Plasmid (h) - sc-417052 from Santa Cruz Biotechnology
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MCP-3 HDR Plasmid (h) - sc-417052-HDR from Santa Cruz Biotechnology
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MCP-3 Double Nickase Plasmid (h) - sc-417052-NIC from Santa Cruz Biotechnology
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MCP-3 Double Nickase Plasmid (h2) - sc-417052-NIC-2 from Santa Cruz Biotechnology
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MCP-3 CRISPR Activation Plasmid (h) - sc-417052-ACT from Santa Cruz Biotechnology
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MCP-3 CRISPR Activation Plasmid (h2) - sc-417052-ACT-2 from Santa Cruz Biotechnology
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MCP-3 Lentiviral Activation Particles (h) - sc-417052-LAC from Santa Cruz Biotechnology
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MCP-3 Lentiviral Activation Particles (h2) - sc-417052-LAC-2 from Santa Cruz Biotechnology
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MCP-3 siRNA (h) - sc-72035 from Santa Cruz Biotechnology
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MCP-3 shRNA Plasmid (h) - sc-72035-SH from Santa Cruz Biotechnology
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MCP-3 shRNA (h) Lentiviral Particles - sc-72035-V from Santa Cruz Biotechnology
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CCL7/MCP-3/MARC RNAi - H00006354-R01 from Novus Biologicals
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MISSION® esiRNA - EHU138521 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5622 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5622 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03829 from Sigma-Aldrich
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CCL7 siRNA (Human) - CRH4287 from Cohesion Biosciences
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CCL7 - MBS8239362 from MyBioSource
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shRNA set against Human CCL7 (NM_006273.2) - SHH257717 from Creative biogene
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shRNA set against Human CCL7(NM_006273.2) - SHG151417 from Creative biogene
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Human CCL7 siRNA - orb264789 from Biorbyt
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CCL7 shRNA Plasmid (Human) - CHH4287 from Cohesion Biosciences
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CCL7 miRNA 3'UTR clone - MiUTR1H-01809 from Creative biogene
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