Gene Symbol | WSB1 |
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Entrez Gene | 26118 |
Alt Symbol | SWIP1, WSB-1 |
Species | Human |
Gene Type | protein-coding |
Description | WD repeat and SOCS box containing 1 |
Other Description | SOCS box-containing WD protein SWiP-1|WD repeat and SOCS box-containing 1|WD repeat and SOCS box-containing protein 1 |
Swissprots | Q9UBH9 Q9Y6I7 Q9UNN6 Q9UG25 Q9Y656 Q9NRB1 |
Accessions | EAW51026 EAW51027 EAW51028 EAW51029 EAW51030 EAW51031 Q9Y6I7 AF069313 AAD20954 AF072880 AAD28808 AF106683 AAD43036 AF106684 AAD43037 AF112205 AAF17193 AF147442 AF240696 AAF82746 AK057082 AK074917 BAC11291 AK091514 AK222576 BAD96296 AK294516 BAG57729 AK300262 BAG62023 AK307114 AL110243 CAB53693 AL110269 CAB53708 AM393409 CAL38287 AM393665 CAL38541 BC005226 AAH05226 BC021110 AAH21110 BC048007 BU189299 HQ447739 ADQ32224 XM_005257963 XP_005258020 XM_011524605 XP_011522907 NM_015626 NP_056441 NM_134265 NP_599027 NM_134264 |
Function | Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes type II iodothyronine deiodinase/DIO2. Confers constitutive instability to HIPK2 through proteasomal degradation. {ECO:0000269|PubMed:15601820, ECO:0000269|PubMed:15965468, ECO:0000269|PubMed:18093972}. |
WSB1 CRISPR/Cas9 KO Plasmid (h) - sc-411879 from Santa Cruz Biotechnology
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WSB1 HDR Plasmid (h) - sc-411879-HDR from Santa Cruz Biotechnology
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WSB1 Double Nickase Plasmid (h) - sc-411879-NIC from Santa Cruz Biotechnology
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WSB1 Double Nickase Plasmid (h2) - sc-411879-NIC-2 from Santa Cruz Biotechnology
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WSB1 CRISPR Activation Plasmid (h) - sc-411879-ACT from Santa Cruz Biotechnology
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WSB1 CRISPR Activation Plasmid (h2) - sc-411879-ACT-2 from Santa Cruz Biotechnology
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WSB1 Lentiviral Activation Particles (h) - sc-411879-LAC from Santa Cruz Biotechnology
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WSB1 Lentiviral Activation Particles (h2) - sc-411879-LAC-2 from Santa Cruz Biotechnology
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WSB1 siRNA (h) - sc-93766 from Santa Cruz Biotechnology
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WSB1 shRNA Plasmid (h) - sc-93766-SH from Santa Cruz Biotechnology
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WSB1 shRNA (h) Lentiviral Particles - sc-93766-V from Santa Cruz Biotechnology
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WSB1 RNAi - H00026118-R01 from Novus Biologicals
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WSB1 RNAi - H00026118-R02 from Novus Biologicals
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MISSION® esiRNA - EHU071901 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22932 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22932 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09122 from Sigma-Aldrich
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WSB1 siRNA (Human) - CRH8716 from Cohesion Biosciences
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WSB1 - MBS8215494 from MyBioSource
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shRNA set against Human WSB1 (NM_015626.8) - SHH447476 from Creative biogene
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shRNA set against Human WSB1(NM_015626.8) - SHL136772 from Creative biogene
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shRNA set against Human WSB1(NM_134265.2) - SHL136836 from Creative biogene
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shRNA set against Human WSB1(NM_015626.8) - SHL136886 from Creative biogene
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WSB1 shRNA Plasmid (Human) - CHH8716 from Cohesion Biosciences
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WSB1 miRNA 3'UTR clone - MiUTR1H-11289 from Creative biogene
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