| Gene Symbol | Il4i1 |
|---|---|
| Entrez Gene | 14204 |
| Alt Symbol | Fig1, Fig1-ps, LAAO, LAO |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | interleukin 4 induced 1 |
| Other Description | IL4-induced protein 1|L-amino acid oxidase|L-amino-acid oxidase|interleukin-4-induced protein 1|interleukin-four induced gene 1|interleukin-four induced gene-1 protein|interleukin-four induced protein-1|protein Fig-1 |
| Swissprots | Q6YBV6 Q3U7S6 Q1LZI6 Q9CXK7 O09046 Q6YDI8 Q3V0K2 Q6Y632 Q8R2G8 Q3T9N9 |
| Accessions | AAB51354 AAM15529 AAM15530 AAO17038 AAO23118 AAO65453 AAS00457 EDL22757 O09046 AK014297 BAB29253 AK150582 BAE29676 AK151030 BAE30047 AK151171 BAE30174 AK151731 AK152538 BAE31293 AK157036 AK172393 BAE42981 AY157538 AAO17039 BC050205 BC115960 AAI15961 U70429 AAB51353 U89428 AAC36534 U89429 AAC36535 NM_010215 NP_034345 |
| Function | Lysosomal L-amino-acid oxidase with highest specific activity with phenylalanine. May play a role in lysosomal antigen processing and presentation. {ECO:0000269|PubMed:15383589}. |
| Subcellular Location | Isoform 1: Lysosome. |
| Tissue Specificity | Isoform 1 primarily found in immune tissues, mostly in B-lymphocytes. Isoform 2 restricted to the testis, predominantly in Sertoli cells at the periphery of the ducts, and the brain, including Purkinje cells, hippocampus and mitral cells in the olfactory bulb. No isoform 2 expression in fetal tissues. {ECO:0000269|PubMed:16029492}. |
| Top Pathways | Cysteine and methionine metabolism, Phenylalanine metabolism, Tyrosine metabolism, Tryptophan metabolism, Alanine, aspartate and glutamate metabolism |