Gene Symbol | PDE1C |
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Entrez Gene | 5137 |
Alt Symbol | Hcam3, cam-PDE 1C, hCam-3 |
Species | Human |
Gene Type | protein-coding |
Description | phosphodiesterase 1C, calmodulin-dependent 70kDa |
Other Description | Human 3',5' cyclic nucleotide phosphodiesterase (HSPDE1C1A)|calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C |
Swissprots | Q14124 B3KPC6 Q14123 Q8NB10 E9PE92 |
Accessions | AAC29142 AAS07516 EAW93984 EAW93985 EAW93986 EAW93987 Q14123 AK056170 BAG51638 AK091734 BAC03734 AK094180 BAG52838 AK125029 AK126467 BC022479 AAH22479 BC022525 AAH22525 BQ020305 DA023468 DA025688 DA030384 DA221214 DA249465 DQ893643 ABM84569 EU176511 ABW03312 U40371 AAC50437 U40372 AAA96961 XM_005249768 XP_005249825 XM_011515410 XP_011513712 XM_011515411 XP_011513713 XM_011515412 XP_011513714 XM_011515413 XP_011513715 XM_011515414 XP_011513716 NM_001191056 NP_001177985 NM_001191057 NP_001177986 NM_001191058 NP_001177987 NM_001191059 NP_001177988 NM_005020 NP_005011 |
Function | Cyclic nucleotide phosphodiesterase with a dual- specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a high affinity for both cAMP and cGMP. |
Tissue Specificity | Expressed in several tissues, including brain and heart. |
Top Pathways | Olfactory transduction, Calcium signaling pathway, Morphine addiction, Purine metabolism |
PDE1C CRISPR/Cas9 KO Plasmid (h) - sc-417068 from Santa Cruz Biotechnology
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PDE1C HDR Plasmid (h) - sc-417068-HDR from Santa Cruz Biotechnology
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PDE1C Double Nickase Plasmid (h) - sc-417068-NIC from Santa Cruz Biotechnology
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PDE1C Double Nickase Plasmid (h2) - sc-417068-NIC-2 from Santa Cruz Biotechnology
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PDE1C CRISPR Activation Plasmid (h) - sc-417068-ACT from Santa Cruz Biotechnology
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PDE1C CRISPR Activation Plasmid (h2) - sc-417068-ACT-2 from Santa Cruz Biotechnology
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PDE1C Lentiviral Activation Particles (h) - sc-417068-LAC from Santa Cruz Biotechnology
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PDE1C Lentiviral Activation Particles (h2) - sc-417068-LAC-2 from Santa Cruz Biotechnology
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PDE1C siRNA (h) - sc-62765 from Santa Cruz Biotechnology
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PDE1C shRNA Plasmid (h) - sc-62765-SH from Santa Cruz Biotechnology
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PDE1C shRNA (h) Lentiviral Particles - sc-62765-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU058921 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16532 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16532 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06102 from Sigma-Aldrich
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PDE1C siRNA (Human) - CRH3417 from Cohesion Biosciences
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shRNA set against Human PDE1C (NM_005020.2) - SHH372380 from Creative biogene
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Human PDE1C siRNA - orb263919 from Biorbyt
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PDE1C shRNA Plasmid (Human) - CHH3417 from Cohesion Biosciences
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PDE1C miRNA 3'UTR clone - MiUTR3H-05513 from Creative biogene
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