Hcn2

Gene Symbol Hcn2
Entrez Gene 15166
Alt Symbol BCNG2, HAC1, trls
Species Mouse
Gene Type protein-coding
Description hyperpolarization-activated, cyclic nucleotide-gated K+ 2
Other Description BCNG-2|HAC-1|brain cyclic nucleotide-gated channel 2|hyperpolarization-activated cation channel 1|potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
Swissprots O88703 O70506
Accessions AAG43529 EDL31671 O88703 AB154248 BAI44633 AF064873 AAC40125 AJ225122 CAA12406 BC156149 AAI56150 CX242892 NM_008226 NP_032252
Function Hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions. Contributes to the native pacemaker currents in heart (If) and in neurons (Ih). Can also transport ammonium in the distal nephron. Produces a large instantaneous current. {ECO:0000269|PubMed:10962006, ECO:0000269|PubMed:11096117, ECO:0000269|PubMed:11741901, ECO:0000269|PubMed:12034718, ECO:0000269|PubMed:12193608, ECO:0000269|PubMed:12968185, ECO:0000269|PubMed:17562314, ECO:0000269|PubMed:23103389}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:10962006, ECO:0000269|PubMed:11096117, ECO:0000269|PubMed:12034718, ECO:0000269|PubMed:12193608, ECO:0000269|PubMed:17562314, ECO:0000269|PubMed:23103389}; Multi-pass membrane protein {ECO:0000269|PubMed:10962006, ECO:0000269|PubMed:11096117, ECO:0000269|PubMed:12034718, ECO:0000269|PubMed:12193608, ECO:0000269|PubMed:17562314, ECO:0000269|PubMed:23103389}.
Tissue Specificity Highly expressed in brain. Detected at low levels in heart, in ventricle, atrium and in sinoatrial node (SAN). {ECO:0000269|PubMed:9630217}.
Top Pathways cAMP signaling pathway

hyperpolarization activated cyclic nucleotide-gated potassium channel 2, ELISA Kit - MBS9320525 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 ELISA Kit - EKE55148 from Biomatik

Category ELISA Kit
Prices $809.60, $3,440.80, $6,476.80
Sizes 96 t, 5x96t, 10x96t
Range 0.312-20 ng/mL

Hcn2 - EKM1288 from Nordic BioSite

Sensitivity 0.188ng/ml
Range 0.312-20ng/ml

HCN2 ELISA Kit (Mouse) : 96 Wells (OKEH02482) - OKEH02482 from Aviva Systems Biology

Category ELISA Kit
Prices $480.00
Sizes 96 wells
Sensitivity < 0.091 ng/mL
Range 0.312 - 20 ng/mL

Mouse Hcn2 ELISA Kit - E056166 from Biobool

Category ELISA Kit

Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 ELISA Kit - EK3626 from Signalway Antibody

Category ELISA Kit
Prices $739.00
Sizes 1x96t
Range 0.312-20 ng/mL

Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2, ELISA Kit - MBS9427460 from MyBioSource

Category ELISA Kit
Prices $670.00
Sizes 96 tests
Range 0.312-20 ng/mL

Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2, ELISA Kit - MBS765267 from MyBioSource

Category ELISA Kit
Prices $295.00, $390.00, $1,615.00, $3,015.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.188ng/ml
Range 0.312-20ng/ml

Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2, ELISA Kit - MBS288871 from MyBioSource

Category ELISA Kit
Prices $430.00, $570.00, $2,515.00, $4,520.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Range 0.312-20 ng/mL
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