| Gene Symbol |
RNF149
|
| Entrez Gene |
284996
|
| Alt Symbol |
DNAPTP2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ring finger protein 149
|
| Other Description |
DNA polymerase-transactivated protein 2|E3 ubiquitin-protein ligase RNF149
|
| Swissprots |
Q8NBY5 Q8N5I8 Q8NC42 Q8WUU3 Q53S14
|
| Accessions |
AAY14775 AAY15089 CAF86191 EAX01817 EAX01818 EAX01819 EAX01820 Q8NC42 AK074985 BAC11334 AK075141 BAC11430 AK129799 AM392566 CAL37444 AY450390 AAR21083 BC019355 AAH19355 BC032328 AAH32328 BC045743 AAH45743 DA383672 XM_005263920 XP_005263977 XM_005263921 XP_005263978 XM_011510990 XP_011509292 XR_244888 XR_922908 XR_922909 NM_173647 NP_775918
|
| Function |
E3 ubiquitin-protein ligase. Ubiquitinates BRAF, inducing its proteasomal degradation. {ECO:0000269|PubMed:22628551}.
|
| Subcellular Location |
Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
|