Gene Symbol |
ACTR5
|
Entrez Gene |
79913
|
Alt Symbol |
Arp5, INO80M
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
ARP5 actin-related protein 5 homolog (yeast)
|
Other Description |
INO80 complex subunit M|actin-related protein 5|hARP5|sarcoma antigen NY-SAR-16
|
Swissprots |
Q8IUY5 Q9BRN0 Q9BVB7 Q8N724 Q86WF7 Q9H9F9
|
Accessions |
EAW76010 EAW76011 Q9H9F9 AK022847 BAB14270 AY211911 AAO65164 BC001324 AAH01324 BC006162 AAH06162 BC038402 AAH38402 BF529768 XM_005260554 XP_005260611 XM_005260555 XP_005260612 XM_005260557 XP_005260614 XM_011529047 XP_011527349 NM_024855 NP_079131
|
Function |
Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. Involved in DNA double-strand break repair and UV-damage excision repair. {ECO:0000269|PubMed:19014934, ECO:0000269|PubMed:20855601}.
|
Subcellular Location |
Nucleus. Cytoplasm. Note=Predominantly nuclear but undergoes nucleo-cytoplasmic shuttling. Localized to interphase nuclei, but not nucleoli; excluded from chromosomes as mitosis progresses.
|