Gene Symbol | CDC7 |
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Entrez Gene | 8317 |
Alt Symbol | CDC7L1, HsCDC7, Hsk1, huCDC7 |
Species | Human |
Gene Type | protein-coding |
Description | cell division cycle 7 |
Other Description | CDC7 (cell division cycle 7, S. cerevisiae, homolog)-like 1|CDC7-related kinase|cell division cycle 7 homolog|cell division cycle 7-like protein 1|cell division cycle 7-related protein kinase |
Swissprots | Q5T5U5 D3DT31 O00558 O00311 |
Accessions | AAS79323 EAW73114 EAW73115 O00311 AB003698 BAA19962 AB209337 BAD92574 AF005209 AAB97512 AF015592 AAC52080 AI672674 AK298963 BAH12913 AK312726 BAG35599 AY312583 AAR16187 BC110526 AAI10527 BC110527 AAI10528 BC111044 AAI11045 DA127303 DA791490 N62245 XM_005271241 XP_005271298 XM_005271244 XP_005271301 XM_005271245 XP_005271302 XM_011542226 XP_011540528 XM_011542227 XP_011540529 NM_001134419 NP_001127891 NM_001134420 NP_001127892 NM_003503 NP_003494 |
Function | Seems to phosphorylate critical substrates that regulate the G1/S phase transition and/or DNA replication. Can phosphorylates MCM2 and MCM3. {ECO:0000269|PubMed:12065429}. |
Subcellular Location | Nucleus. |
Top Pathways | Cell cycle |
Cdc7 CRISPR/Cas9 KO Plasmid (h) - sc-402191 from Santa Cruz Biotechnology
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Cdc7 HDR Plasmid (h) - sc-402191-HDR from Santa Cruz Biotechnology
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Cdc7 Double Nickase Plasmid (h) - sc-402191-NIC from Santa Cruz Biotechnology
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Cdc7 Double Nickase Plasmid (h2) - sc-402191-NIC-2 from Santa Cruz Biotechnology
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Cdc7 CRISPR Activation Plasmid (h) - sc-402191-ACT from Santa Cruz Biotechnology
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Cdc7 CRISPR Activation Plasmid (h2) - sc-402191-ACT-2 from Santa Cruz Biotechnology
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Cdc7 Lentiviral Activation Particles (h) - sc-402191-LAC from Santa Cruz Biotechnology
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Cdc7 Lentiviral Activation Particles (h2) - sc-402191-LAC-2 from Santa Cruz Biotechnology
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Cdc7 siRNA (h) - sc-37549 from Santa Cruz Biotechnology
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Cdc7 shRNA Plasmid (h) - sc-37549-SH from Santa Cruz Biotechnology
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Cdc7 shRNA (h) Lentiviral Particles - sc-37549-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU012161 from Sigma-Aldrich
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MISSION® siRNA - SIHK0333 from Sigma-Aldrich
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MISSION® siRNA - SIHK0334 from Sigma-Aldrich
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MISSION® siRNA - SIHK0332 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5796 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5796 from Sigma-Aldrich
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CDC7 siRNA (Human) - CRH5440 from Cohesion Biosciences
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CDC7 RNAi - H00008317-R02 from Novus Biologicals
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CDC7 - MBS8205589 from MyBioSource
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shRNA set against Human CDC7 (NM_003503.3) - SHH259981 from Creative biogene
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Human CDC7 siRNA - orb265942 from Biorbyt
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CDC7 shRNA Plasmid (Human) - CHH5440 from Cohesion Biosciences
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CDC7 miRNA 3'UTR clone - MiUTR3H-05852 from Creative biogene
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CDC7 miRNA 3'UTR clone - MiUTR3H-05853 from Creative biogene
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