| Gene Symbol |
C11orf73
|
| Entrez Gene |
51501
|
| Alt Symbol |
HSPC138, HSPC179, Hikeshi, L7RN6, OPI10
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
chromosome 11 open reading frame 73
|
| Other Description |
lethal, Chr 7, Rinchik 6|protein Hikeshi
|
| Swissprots |
Q9P0N1 Q9NZZ1 Q53FT3 Q9P022 Q9NVQ2 Q8WVE8
|
| Accessions |
EAW75133 EAW75134 EAW75135 EAW75136 EAW75137 Q53FT3 AA148558 AF151082 AAF36168 AF161487 AAF29102 AF161527 AAF29142 AK001447 BAA91698 AK125010 AK223198 BAD96918 AK298763 BAG60905 BC001677 AAH01677 BC006476 AAH06476 BC015991 AAH15991 BC018080 AAH18080 BC021621 AAH21621 BE858273 BP423222 BX332668 DQ892731 ABM83657 DQ895977 ABM86903 XM_011545097 XP_011543399 XR_949963 NM_016401 NP_057485 NR_024596 NR_024597 NR_024598
|
| Function |
Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus. {ECO:0000269|PubMed:22541429}.
|
| Subcellular Location |
Cytoplasm, cytosol {ECO:0000269|PubMed:22541429}. Nucleus {ECO:0000269|PubMed:22541429}.
|