Gene Symbol | COQ4 |
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Entrez Gene | 51117 |
Alt Symbol | CGI-92, COQ10D7 |
Species | Human |
Gene Type | protein-coding |
Description | coenzyme Q4 |
Other Description | coenzyme Q biosynthesis protein 4 homolog|coenzyme Q4 homolog|ubiquinone biosynthesis protein COQ4 homolog, mitochondrial |
Swissprots | Q5T4B8 B2R958 Q96EW4 A8WBK8 Q9Y3A0 |
Accessions | CBN61894 EAW87774 EAW87775 EAW87776 EAW87777 EAW87778 Q9Y3A0 AF151850 AAD34087 AK025376 AK095083 AK128853 AK301333 BAG62881 AK313650 BAG36405 AM392657 CAL37535 BC011895 AAH11895 BC036603 BP365109 CB111694 CX787359 EU216419 ABW91141 EU216420 ABW91142 EU216421 ABW91143 EU216422 ABW91144 EU216423 ABW91145 XM_011518761 XP_011517063 XR_929805 NM_001305942 NP_001292871 NM_016035 NP_057119 |
Function | Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides. {ECO:0000255|HAMAP- Rule:MF_03111, ECO:0000269|PubMed:18474229}. |
Subcellular Location | Isoform 1: Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. |
Tissue Specificity | Expressed ubiquitously, but at high levels in liver, lung and pancreas. {ECO:0000269|PubMed:18474229}. |
COQ4 CRISPR/Cas9 KO Plasmid (h) - sc-408432 from Santa Cruz Biotechnology
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COQ4 HDR Plasmid (h) - sc-408432-HDR from Santa Cruz Biotechnology
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COQ4 Double Nickase Plasmid (h) - sc-408432-NIC from Santa Cruz Biotechnology
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COQ4 Double Nickase Plasmid (h2) - sc-408432-NIC-2 from Santa Cruz Biotechnology
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COQ4 CRISPR Activation Plasmid (h) - sc-408432-ACT from Santa Cruz Biotechnology
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COQ4 CRISPR Activation Plasmid (h2) - sc-408432-ACT-2 from Santa Cruz Biotechnology
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COQ4 Lentiviral Activation Particles (h) - sc-408432-LAC from Santa Cruz Biotechnology
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COQ4 Lentiviral Activation Particles (h2) - sc-408432-LAC-2 from Santa Cruz Biotechnology
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COQ4 siRNA (h) - sc-72975 from Santa Cruz Biotechnology
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COQ4 shRNA Plasmid (h) - sc-72975-SH from Santa Cruz Biotechnology
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COQ4 shRNA (h) Lentiviral Particles - sc-72975-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU008871 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6446 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6446 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03357 from Sigma-Aldrich
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COQ4 siRNA (Human) - CRH9537 from Cohesion Biosciences
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COQ4 - MBS8208010 from MyBioSource
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shRNA set against Human COQ4 (NM_016035.3) - SHH267973 from Creative biogene
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shRNA set against Human COQ4(NM_016035.3) - SHG193375 from Creative biogene
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Human COQ4 siRNA - orb270039 from Biorbyt
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COQ4 shRNA Plasmid (Human) - CHH9537 from Cohesion Biosciences
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COQ4 miRNA 3'UTR clone - MiUTR1H-02367 from Creative biogene
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