Gene Symbol | FAM83D |
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Entrez Gene | 81610 |
Alt Symbol | C20orf129, CHICA, dJ616B8.3 |
Species | Human |
Gene Type | protein-coding |
Description | family with sequence similarity 83, member D |
Other Description | protein FAM83D|spindle protein CHICA |
Swissprots | Q96N89 Q6P457 Q9BVM8 Q5THR2 Q9H4H8 Q68EN1 Q7Z6H0 Q96DF5 B4E1I7 |
Accessions | CAK32200 EAW76008 Q9H4H8 AK055793 BAB71016 AK095660 AK303860 BAG64799 AL832274 BC001068 AAH01068 BC006553 AAH06553 BC053683 AAH53683 BC063661 AAH63661 BC080188 AAH80188 XM_011529073 XP_011527375 NM_030919 NP_112181 |
Function | Required for proper chromosome congression and alignment during mitosis. Required for targeting KIF22/KID to the spindle microtubules. {ECO:0000269|PubMed:18485706}. |
Subcellular Location | Cytoplasm. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=Primarily cytoplasmic during interphase, but beginning in prophase, associates with spindle microtubules, with a clear concentration toward the spindle poles. It persists on spindle microtubules through metaphase and anaphase. |
FAM83D CRISPR/Cas9 KO Plasmid (h) - sc-408291 from Santa Cruz Biotechnology
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FAM83D HDR Plasmid (h) - sc-408291-HDR from Santa Cruz Biotechnology
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FAM83D Double Nickase Plasmid (h) - sc-408291-NIC from Santa Cruz Biotechnology
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FAM83D Double Nickase Plasmid (h2) - sc-408291-NIC-2 from Santa Cruz Biotechnology
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FAM83D CRISPR Activation Plasmid (h) - sc-408291-ACT from Santa Cruz Biotechnology
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FAM83D CRISPR Activation Plasmid (h2) - sc-408291-ACT-2 from Santa Cruz Biotechnology
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FAM83D Lentiviral Activation Particles (h) - sc-408291-LAC from Santa Cruz Biotechnology
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FAM83D Lentiviral Activation Particles (h2) - sc-408291-LAC-2 from Santa Cruz Biotechnology
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FAM83D siRNA (h) - sc-77311 from Santa Cruz Biotechnology
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FAM83D shRNA Plasmid (h) - sc-77311-SH from Santa Cruz Biotechnology
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FAM83D shRNA (h) Lentiviral Particles - sc-77311-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU084291 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN8428 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8428 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05220 from Sigma-Aldrich
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FAM83D siRNA (Human) - CRJ3020 from Cohesion Biosciences
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FAM83D - MBS8240521 from MyBioSource
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shRNA set against Human FAM83D (NM_030919.2) - SHH291949 from Creative biogene
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Human FAM83D siRNA - orb273521 from Biorbyt
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FAM83D shRNA Plasmid (Human) - CHJ3020 from Cohesion Biosciences
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FAM83D miRNA 3'UTR clone - MiUTR1H-03485 from Creative biogene
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