Gene Symbol | TCEA1 |
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Entrez Gene | 6917 |
Alt Symbol | GTF2S, SII, TCEA, TF2S, TFIIS |
Species | Human |
Gene Type | protein-coding |
Description | transcription elongation factor A (SII), 1 |
Other Description | transcription elongation factor A protein 1|transcription elongation factor S-II protein 1|transcription elongation factor TFIIS.o |
Swissprots | Q15563 A6NF25 Q6FG87 A8K339 P23193 |
Accessions | EAW86739 EAW86740 EAW86741 P23193 AK026617 AK094425 AK290454 BAF83143 AK297729 BAH12657 AK297957 BAH12696 AU125645 AU280634 BC072460 AAH72460 BM477937 BQ016366 BT019995 AAV38798 BX538034 CR542221 CAG47017 DA021678 DB091231 M81601 AAA61138 X57198 CAA40484 X62585 CAA44470 XM_006716467 XP_006716530 XM_011517578 XP_011515880 XM_011517579 XP_011515881 NM_006756 NP_006747 NM_201437 NP_958845 NR_109901 NR_109902 |
Function | Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus. |
Subcellular Location | Nucleus. |
TCEA1 CRISPR/Cas9 KO Plasmid (h) - sc-405531 from Santa Cruz Biotechnology
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TCEA1 HDR Plasmid (h) - sc-405531-HDR from Santa Cruz Biotechnology
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TCEA1 Double Nickase Plasmid (h) - sc-405531-NIC from Santa Cruz Biotechnology
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TCEA1 Double Nickase Plasmid (h2) - sc-405531-NIC-2 from Santa Cruz Biotechnology
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TCEA1 CRISPR Activation Plasmid (h) - sc-405531-ACT from Santa Cruz Biotechnology
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TCEA1 CRISPR Activation Plasmid (h2) - sc-405531-ACT-2 from Santa Cruz Biotechnology
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TCEA1 Lentiviral Activation Particles (h) - sc-405531-LAC from Santa Cruz Biotechnology
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TCEA1 Lentiviral Activation Particles (h2) - sc-405531-LAC-2 from Santa Cruz Biotechnology
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TCEA1 siRNA (h) - sc-63109 from Santa Cruz Biotechnology
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TCEA1 shRNA Plasmid (h) - sc-63109-SH from Santa Cruz Biotechnology
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TCEA1 shRNA (h) Lentiviral Particles - sc-63109-V from Santa Cruz Biotechnology
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TCEA1 RNAi - H00006917-R02 from Novus Biologicals
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TCEA1 RNAi - H00006917-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN21119 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21119 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10328 from Sigma-Aldrich
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TCEA1 siRNA (Human) - CRH4741 from Cohesion Biosciences
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TCEA1 - MBS829588 from MyBioSource
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shRNA set against Human Tcea1 (NM_006756.2) - SHH424548 from Creative biogene
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shRNA set against Human TCEA1(NM_006756.2) - SHL060816 from Creative biogene
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shRNA set against Human TCEA1(NM_201437.1) - SHL060902 from Creative biogene
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Human TCEA1 siRNA - orb265243 from Biorbyt
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TCEA1 shRNA Plasmid (Human) - CHH4741 from Cohesion Biosciences
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TCEA1 miRNA 3'UTR clone - MiUTR1H-10252 from Creative biogene
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TCEA1 miRNA 3'UTR clone - MiUTR1H-10253 from Creative biogene
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