ATP2B3

Gene Symbol ATP2B3
Entrez Gene 492
Alt Symbol CFAP39, CLA2, OPCA, PMCA3, PMCA3a, SCAX1
Species Human
Gene Type protein-coding
Description ATPase, Ca++ transporting, plasma membrane 3
Other Description cilia and flagella associated protein 39|plasma membrane calcium ATPase|plasma membrane calcium pump|plasma membrane calcium-transporting ATPase 3
Swissprots B7WNR8 B7WNY5 Q12995 Q16858 Q16720
Accessions EAW72858 EAW72859 EAW72860 Q16720 AK090838 AK094500 AK130194 BAC85302 AK307765 AK308705 BC047580 BC130009 AAI30010 BG739902 BM680649 BM695792 BM805938 BM986989 BQ878721 BU183973 BU790224 BU790521 DQ201779 ABG24243 U15689 AAA60986 U15690 AAA60987 U57971 AAB09762 U60414 AAB38530 XM_005274689 XP_005274746 XM_005274690 XP_005274747 XM_005274691 XP_005274748 XM_005274692 XP_005274749 XM_011531174 XP_011529476 XM_011531175 XP_011529477 XM_011531176 XP_011529478 XM_011531177 XP_011529479 NM_001001344 NP_001001344 NM_021949 NP_068768
Function This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell.
Subcellular Location Cell membrane; Multi-pass membrane protein.
Tissue Specificity Highly expressed in the cerebellum, particulary in the presynaptic terminals of parallel fibers- Purkinje neurons. Isoform XE and isoform XB are the most abundant isoforms and are detected at low levels in brain and fetal skeletal muscle. The other isoforms are only found at lower levels and not in fetal tissues. {ECO:0000269|PubMed:22912398}.
Top Pathways Calcium signaling pathway, Salivary secretion, Pancreatic secretion, Adrenergic signaling in cardiomyocytes, cGMP-PKG signaling pathway

PMCA3 CRISPR/Cas9 KO Plasmid (h) - sc-404464 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PMCA3 HDR Plasmid (h) - sc-404464-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PMCA3 Double Nickase Plasmid (h) - sc-404464-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PMCA3 Double Nickase Plasmid (h2) - sc-404464-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PMCA3 CRISPR Activation Plasmid (h) - sc-404464-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PMCA3 CRISPR Activation Plasmid (h2) - sc-404464-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PMCA3 Lentiviral Activation Particles (h) - sc-404464-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PMCA3 Lentiviral Activation Particles (h2) - sc-404464-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PMCA3 siRNA (h) - sc-42600 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PMCA3 shRNA Plasmid (h) - sc-42600-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PMCA3 shRNA (h) Lentiviral Particles - sc-42600-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PMCA3 RNAi - H00000492-R04 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

PMCA3 RNAi - H00000492-R03 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU080941 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1855 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1855 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR11894 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr11894

ATP2B3 siRNA (Human) - CRH0346 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ATP2B3 - MBS8222969 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ATP2B3 (NM_021949.3) - SHH242662 from Creative biogene

Category siRNA
Species Reactivities Human

Human ATP2B3 siRNA - orb260848 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ATP2B3 shRNA Plasmid (Human) - CHH0346 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ATP2B3 miRNA 3'UTR clone - MiUTR4H-TG00607 from Creative biogene

Species Reactivities Human
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