Gene Symbol | VRK3 |
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Entrez Gene | 51231 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | vaccinia related kinase 3 |
Other Description | inactive serine/threonine-protein kinase VRK3|serine/threonine-protein kinase VRK3|serine/threonine-protein pseudokinase VRK3|vaccinia-related kinase 3 |
Swissprots | Q9P2V8 Q502Y2 A8KA53 A6NEG5 Q8IV63 |
Accessions | EAW52588 EAW52589 EAW52590 EAW52591 EAW52592 Q8IV63 AB031052 BAA90769 AF514788 AAP47180 AK074461 AK123892 AK125747 AK225154 AK292918 BAF85607 AK294802 BAG57922 AK303010 BAG64141 AK303529 BAG64557 AK311220 AV706241 BC003546 BC023556 AAH23556 BC095449 AAH95449 BG421578 BP335032 XM_005258971 XP_005259028 XM_005258972 XP_005259029 XM_005258974 XP_005259031 XM_006723237 XP_006723300 XM_006723238 XP_006723301 XM_011527023 XP_011525325 XR_243939 XR_935834 NM_001025778 NP_001020949 NM_001308420 NP_001295349 NM_016440 NP_057524 |
Function | Inactive kinase that suppresses ERK activity by promoting phosphatase activity of DUSP3 which specifically dephosphorylates and inactivates ERK in the nucleus. {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:14645249}. |
VRK3 CRISPR/Cas9 KO Plasmid (h) - sc-406134 from Santa Cruz Biotechnology
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VRK3 HDR Plasmid (h) - sc-406134-HDR from Santa Cruz Biotechnology
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VRK3 Double Nickase Plasmid (h) - sc-406134-NIC from Santa Cruz Biotechnology
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VRK3 Double Nickase Plasmid (h2) - sc-406134-NIC-2 from Santa Cruz Biotechnology
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VRK3 CRISPR Activation Plasmid (h) - sc-406134-ACT from Santa Cruz Biotechnology
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VRK3 CRISPR Activation Plasmid (h2) - sc-406134-ACT-2 from Santa Cruz Biotechnology
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VRK3 Lentiviral Activation Particles (h) - sc-406134-LAC from Santa Cruz Biotechnology
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VRK3 Lentiviral Activation Particles (h2) - sc-406134-LAC-2 from Santa Cruz Biotechnology
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VRK3 siRNA (h) - sc-97404 from Santa Cruz Biotechnology
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VRK3 shRNA Plasmid (h) - sc-97404-SH from Santa Cruz Biotechnology
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VRK3 shRNA (h) Lentiviral Particles - sc-97404-V from Santa Cruz Biotechnology
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VRK3 RNAi - H00051231-R02 from Novus Biologicals
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MISSION® esiRNA - EHU013641 from Sigma-Aldrich
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MISSION® siRNA - SIHK2455 from Sigma-Aldrich
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MISSION® siRNA - SIHK2457 from Sigma-Aldrich
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MISSION® siRNA - SIHK2456 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22736 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22736 from Sigma-Aldrich
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VRK3 siRNA (Human) - CRH9621 from Cohesion Biosciences
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VRK3 - MBS8200380 from MyBioSource
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shRNA set against Human VRK3 (NM_016440.3) - SHH445168 from Creative biogene
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shRNA set against Human VRK3(NM_016440.3) - SHL128538 from Creative biogene
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shRNA set against Human VRK3(NM_001025778.1) - SHL128602 from Creative biogene
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VRK3 shRNA Plasmid (Human) - CHH9621 from Cohesion Biosciences
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VRK3 miRNA 3'UTR clone - MiUTR1H-11168 from Creative biogene
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