Gene Symbol | TMBIM6 |
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Entrez Gene | 7009 |
Alt Symbol | BAXI1, BI-1, TEGT |
Species | Human |
Gene Type | protein-coding |
Description | transmembrane BAX inhibitor motif containing 6 |
Other Description | bax inhibitor 1|testis enhanced gene transcript|testis-enhanced gene transcript protein|transmembrane BAX inhibitor motif-containing protein 6 |
Swissprots | Q96J50 Q643A7 P55061 O14938 F8W034 B2R5M4 |
Accessions | CAH05396 EAW58089 EAW58090 EAW58091 EAW58092 EAW58093 P55061 AA057740 AF033095 AAB87479 AK026605 AK124849 BAG54105 AK130050 AK130462 AK225804 AK299587 BAH13075 AK304577 BAH14220 AK312238 BAG35171 AY736129 AAU29521 BC000916 AAH00916 BC036203 AAH36203 BQ613936 DA476870 DC319835 DC349385 X75861 CAA53472 XM_005269126 XP_005269183 NM_001098576 NP_001092046 NM_003217 NP_003208 |
Function | Suppressor of apoptosis. Modulates unfolded protein response signaling. Modulate ER calcium homeostasis by acting as a calcium-leak channel. {ECO:0000269|PubMed:21075086, ECO:0000269|PubMed:22128171}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:21075086, ECO:0000269|PubMed:22128171}; Multi- pass membrane protein {ECO:0000269|PubMed:21075086, ECO:0000269|PubMed:22128171}. |
Tissue Specificity | Highly abundant in testis. |
BI-1 CRISPR/Cas9 KO Plasmid (h) - sc-404349 from Santa Cruz Biotechnology
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BI-1 HDR Plasmid (h) - sc-404349-HDR from Santa Cruz Biotechnology
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BI-1 Double Nickase Plasmid (h) - sc-404349-NIC from Santa Cruz Biotechnology
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BI-1 Double Nickase Plasmid (h2) - sc-404349-NIC-2 from Santa Cruz Biotechnology
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BI-1 CRISPR Activation Plasmid (h) - sc-404349-ACT from Santa Cruz Biotechnology
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BI-1 CRISPR Activation Plasmid (h2) - sc-404349-ACT-2 from Santa Cruz Biotechnology
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BI-1 Lentiviral Activation Particles (h) - sc-404349-LAC from Santa Cruz Biotechnology
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BI-1 Lentiviral Activation Particles (h2) - sc-404349-LAC-2 from Santa Cruz Biotechnology
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BI-1 siRNA (h) - sc-37298 from Santa Cruz Biotechnology
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BI-1 shRNA Plasmid (h) - sc-37298-SH from Santa Cruz Biotechnology
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BI-1 shRNA (h) Lentiviral Particles - sc-37298-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU055241 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21431 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21431 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10797 from Sigma-Aldrich
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TMBIM6 siRNA (Human) - CRH4786 from Cohesion Biosciences
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TMBIM6 - MBS8206239 from MyBioSource
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shRNA set against Human TMBIM6 (NM_003217.2) - SHH428328 from Creative biogene
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shRNA set against Human TEGT(NM_003217.2) - SHG091744 from Creative biogene
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Human TMBIM6 siRNA - orb265288 from Biorbyt
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TMBIM6 shRNA Plasmid (Human) - CHH4786 from Cohesion Biosciences
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TMBIM6 miRNA 3'UTR clone - MiUTR4H-TG09015 from Creative biogene
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