Gene Symbol | NREP |
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Entrez Gene | 9315 |
Alt Symbol | C5orf13, D4S114, P311, PRO1873, PTZ17, SEZ17 |
Species | Human |
Gene Type | protein-coding |
Description | neuronal regeneration related protein |
Other Description | neuronal protein 3.1|neuronal regeneration related protein homolog|neuronal regeneration-related protein|protein p311 |
Swissprots | D3DSZ8 B7Z5D2 B2RDN8 Q16612 |
Accessions | CAS01768 EAW49019 EAW49020 EAW49021 EAW49022 EAW49023 EAW49024 EAW49025 Q16612 AF119859 AAF69613 AK021624 AK298779 BAH12868 AK307346 AK309667 AK310585 AK315617 BAG37985 AL547663 BC011050 AAH11050 BC019068 AAH19068 BC072013 AAH72013 BC072443 AAH72443 BX649051 CN415439 DA027062 DA078027 DA490948 DA520221 DA526263 DA534424 DA683910 DA694580 DA704824 DA744980 DA752769 DA908653 DA939543 DC365764 U30521 AAA74903 U36189 AAA93255 XM_006714732 XP_006714795 XM_006714733 XP_006714796 NM_001142474 NP_001135946 NM_001142475 NP_001135947 NM_001142476 NP_001135948 NM_001142477 NP_001135949 NM_001142478 NP_001135950 NM_001142479 NP_001135951 NM_001142480 NP_001135952 NM_001142481 NP_001135953 NM_001142482 NP_001135954 NM_001142483 NP_001135955 NM_004772 NP_004763 |
Function | May have roles in neural function. Ectopic expression augments motility of gliomas. Promotes also axonal regeneration (By similarity). May also have functions in cellular differentiation (By similarity). Induces differentiation of fibroblast into myofibroblast and myofibroblast ameboid migration. Increases retinoic-acid regulation of lipid-droplet biogenesis (By similarity). Down-regulates the expression of TGFB1 and TGFB2 but not of TGFB3 (By similarity). May play a role in the regulation of alveolar generation. {ECO:0000250, ECO:0000269|PubMed:11358844, ECO:0000269|PubMed:16229809}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:11358844}. |
Tissue Specificity | Expressed in lung (at protein level). {ECO:0000269|PubMed:16484684}. |
P311 CRISPR/Cas9 KO Plasmid (h) - sc-418011 from Santa Cruz Biotechnology
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P311 HDR Plasmid (h) - sc-418011-HDR from Santa Cruz Biotechnology
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P311 Double Nickase Plasmid (h) - sc-418011-NIC from Santa Cruz Biotechnology
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P311 Double Nickase Plasmid (h2) - sc-418011-NIC-2 from Santa Cruz Biotechnology
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P311 CRISPR Activation Plasmid (h) - sc-418011-ACT from Santa Cruz Biotechnology
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P311 CRISPR Activation Plasmid (h2) - sc-418011-ACT-2 from Santa Cruz Biotechnology
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P311 Lentiviral Activation Particles (h) - sc-418011-LAC from Santa Cruz Biotechnology
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P311 Lentiviral Activation Particles (h2) - sc-418011-LAC-2 from Santa Cruz Biotechnology
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P311 siRNA (h) - sc-91944 from Santa Cruz Biotechnology
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P311 shRNA Plasmid (h) - sc-91944-SH from Santa Cruz Biotechnology
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P311 shRNA (h) Lentiviral Particles - sc-91944-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU014041 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN4968 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4968 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10210 from Sigma-Aldrich
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NREP siRNA (Human) - CRH6162 from Cohesion Biosciences
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NREP shRNA Plasmid (Human) - CHH6162 from Cohesion Biosciences
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NREP miRNA 3'UTR clone - MiUTR3H-09150 from Creative biogene
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NREP miRNA 3'UTR clone - MiUTR3H-09151 from Creative biogene
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NREP miRNA 3'UTR clone - MiUTR3H-09152 from Creative biogene
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NREP miRNA 3'UTR clone - MiUTR3H-09153 from Creative biogene
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NREP miRNA 3'UTR clone - MiUTR3H-09154 from Creative biogene
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NREP miRNA 3'UTR clone - MiUTR3H-09155 from Creative biogene
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NREP miRNA 3'UTR clone - MiUTR3H-09156 from Creative biogene
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NREP miRNA 3'UTR clone - MiUTR3H-09157 from Creative biogene
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