Gene Symbol | EMC4 |
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Entrez Gene | 51234 |
Alt Symbol | PIG17, TMEM85 |
Species | Human |
Gene Type | protein-coding |
Description | ER membrane protein complex subunit 4 |
Other Description | cell proliferation-inducing gene 17 protein|transmembrane protein 85 |
Swissprots | Q96KX9 Q9BUI5 Q9P0T9 B4DJQ4 A8K3A9 Q5J8M3 |
Accessions | CAF86541 EAW92292 EAW92293 EAW92294 Q5J8M3 AF151018 AAF36104 AK075227 BAC11486 AK290524 BAF83213 AK296184 BAG58916 AY336092 AAR24622 BC002583 AAH02583 BC016348 BG707804 DB506932 NM_001286420 NP_001273349 NM_016454 NP_057538 |
Function | May mediate anti-apoptotic activity. |
Subcellular Location | Membrane {ECO:0000269|PubMed:22119785}; Multi-pass membrane protein {ECO:0000269|PubMed:22119785}. |
Tissue Specificity | Isoform 1 is expressed in brain and heart. Isoform 2 is expressed in heart. {ECO:0000269|PubMed:18586032}. |
TMEM85 CRISPR/Cas9 KO Plasmid (h) - sc-412153 from Santa Cruz Biotechnology
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TMEM85 HDR Plasmid (h) - sc-412153-HDR from Santa Cruz Biotechnology
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TMEM85 Double Nickase Plasmid (h) - sc-412153-NIC from Santa Cruz Biotechnology
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TMEM85 Double Nickase Plasmid (h2) - sc-412153-NIC-2 from Santa Cruz Biotechnology
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TMEM85 CRISPR Activation Plasmid (h) - sc-412153-ACT from Santa Cruz Biotechnology
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TMEM85 CRISPR Activation Plasmid (h2) - sc-412153-ACT-2 from Santa Cruz Biotechnology
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TMEM85 Lentiviral Activation Particles (h) - sc-412153-LAC from Santa Cruz Biotechnology
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TMEM85 Lentiviral Activation Particles (h2) - sc-412153-LAC-2 from Santa Cruz Biotechnology
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TMEM85 siRNA (h) - sc-90078 from Santa Cruz Biotechnology
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TMEM85 shRNA Plasmid (h) - sc-90078-SH from Santa Cruz Biotechnology
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TMEM85 shRNA (h) Lentiviral Particles - sc-90078-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU066791 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21670 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21670 from Sigma-Aldrich
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EMC4 siRNA (Human) - CRH9624 from Cohesion Biosciences
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EMC4 - MBS8227232 from MyBioSource
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shRNA set against Human TMEM85 (NM_016454.2) - SHH431024 from Creative biogene
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shRNA set against Human TMEM85(NM_016454.2) - SHL081482 from Creative biogene
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EMC4 shRNA Plasmid (Human) - CHH9624 from Cohesion Biosciences
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EMC4 miRNA 3'UTR clone - MiUTR1H-10559 from Creative biogene
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