| Gene Symbol |
RUVBL2
|
| Entrez Gene |
10856
|
| Alt Symbol |
CGI-46, ECP51, INO80J, REPTIN, RVB2, TIH2, TIP48, TIP49B
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
RuvB-like AAA ATPase 2
|
| Other Description |
48 kDa TATA box-binding protein-interacting protein|48 kDa TBP-interacting protein|51 kDa erythrocyte cytosolic protein|ECP-51|INO80 complex subunit J|RuvB (E coli homolog)-like 2|TAP54-beta|TIP60-associated protein 54-beta|erythrocyte cytosolic protein, 51-KD|repressing pontin 52|reptin52 protein|ruvB-like 2
|
| Swissprots |
Q9Y361 Q6PK27 B3KQ59 E7ETE5 Q6FIB9 Q9Y230
|
| Accessions |
CAE91764 CAF85776 EAW52426 EAW52427 EAW52428 EAW52429 EAW52430 EAW52431 Q9Y230 AB024301 BAA76708 AF124607 AAF87087 AF151804 AAD34041 AF155138 AAD38073 AF401216 AAL02172 AK027762 BAG51374 AK057498 BAG51921 AK074542 BAC11048 AK301344 BAG62892 AL136743 CAB66677 AM393635 CAL38511 BC000428 AAH00428 BC004531 AAH04531 BC008355 AAH08355 CR533507 CAG38538 DQ891392 ABM82318 DQ894568 ABM85494 Y18417 CAB46270 XM_005258426 XP_005258483 XM_005258427 XP_005258484 XM_005258428 XP_005258485 XM_011526330 XP_011524632 NM_006666 NP_006657
|
| Function |
Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.
|
| Subcellular Location |
Nucleus matrix. Nucleus, nucleoplasm. Cytoplasm. Membrane. Note=Mainly localized in the nucleus, associated with nuclear matrix or in the nuclear cytosol. Although it is also present in the cytoplasm and associated with the cell membranes.
|
| Tissue Specificity |
Ubiquitously expressed. Highly expressed in testis and thymus.
|
![Western Blot: RUVBL2 Overexpression Lysate (Adult Normal) [NBL1-15632] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for RUVBL2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/2612_RUVBL2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-15632-img0002.jpg)