| Gene Symbol |
C9orf24
|
| Entrez Gene |
84688
|
| Alt Symbol |
CBE1, NYD-SP22, SMRP1, bA573M23.4
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
chromosome 9 open reading frame 24
|
| Other Description |
ciliated bronchial epithelial protein 1|ciliated bronchial epithelium 1|spermatid-specific manchette-related protein 1|testis development protein NYD-SP22
|
| Swissprots |
Q96LN1 Q96KD1 Q5T599 Q5T5A0 Q8N9G4 Q8NCR6 Q5T598
|
| Accessions |
EAW58456 EAW58457 EAW58458 EAW58459 Q8NCR6 AA338648 AF367474 AAK53410 AK058087 BAB71657 AK094751 BAC04412 AK225981 AW961020 BC022084 AAH22084 BC029484 AAH29484 BI561111 CB854584 HQ447092 ADQ31579 XM_005251616 XP_005251673 XM_005251618 XP_005251675 XM_011518055 XP_011516357 NM_001252195 NP_001239124 NM_032596 NP_115985 NM_147168 NP_671697 NM_147169 NP_671698
|
| Function |
May play a role in spermatogenesis (By similarity). May be involved in differentiation or function of ciliated cells. {ECO:0000250, ECO:0000269|PubMed:15242845}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton {ECO:0000250}. Nucleus {ECO:0000269|PubMed:15242845}. Cytoplasm {ECO:0000269|PubMed:15242845}. Note=Localizes to the manchette in elongating spermatids (By similarity). Predominantly perinuclear in bronchial epithelial cells but also detected in the nucleus in some primary epithelial cells and in a number of cell lines. {ECO:0000250}.
|
| Tissue Specificity |
Expressed in epithelial cells of nasal polyps and in intact epithelium of bronchial biopsies from subjects with and without asthma. Strong expression in columnar cells with little or no expression in basal epithelial cells along the basement membrane. Strongly expressed in ciliated epithelial cells with lower levels in goblet cells (at protein level). {ECO:0000269|PubMed:15242845}.
|
