Gene Symbol | HAUS7 |
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Entrez Gene | 55559 |
Alt Symbol | UCHL5IP, UIP1 |
Species | Human |
Gene Type | protein-coding |
Description | HAUS augmin-like complex, subunit 7 |
Other Description | 26S proteasome-associated UCH37-interacting protein 1|HAUS augmin-like complex subunit 7|UCHL5 interacting protein|X-linked protein STS1769 |
Swissprots | D3DWT9 Q9NP54 Q9UFH9 Q96HS8 B4DUH6 Q99871 |
Accessions | EAW72866 EAW72868 EAW72869 EAW72871 EAW72874 Q99871 AF267739 AAF75785 AK125219 BAC86087 AK296147 BAG58886 AK300650 BAG62338 AK302066 BAG63456 AL122036 CAB59176 AM393157 CAL38035 BC008141 AAH08141 BC047613 BC113839 CA441020 DA272550 DB248557 DQ894946 NM_017518 NP_059988 NR_073156 NM_207106 NM_207107 |
Function | Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex. {ECO:0000269|PubMed:19369198, ECO:0000269|PubMed:19427217}. |
Subcellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Localizes to interphase centrosomes and to mitotic spindle microtubules. |
Tissue Specificity | Detected in spleen, thymus, testis, ovary, small intestine and colon, with highest levels of expression in testis and ovary. {ECO:0000269|PubMed:11163772}. |
UIP1 CRISPR/Cas9 KO Plasmid (h) - sc-407544 from Santa Cruz Biotechnology
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UIP1 HDR Plasmid (h) - sc-407544-HDR from Santa Cruz Biotechnology
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UIP1 Double Nickase Plasmid (h) - sc-407544-NIC from Santa Cruz Biotechnology
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UIP1 Double Nickase Plasmid (h2) - sc-407544-NIC-2 from Santa Cruz Biotechnology
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UIP1 CRISPR Activation Plasmid (h) - sc-407544-ACT from Santa Cruz Biotechnology
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UIP1 CRISPR Activation Plasmid (h2) - sc-407544-ACT-2 from Santa Cruz Biotechnology
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UIP1 Lentiviral Activation Particles (h) - sc-407544-LAC from Santa Cruz Biotechnology
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UIP1 Lentiviral Activation Particles (h2) - sc-407544-LAC-2 from Santa Cruz Biotechnology
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UIP1 siRNA (h) - sc-91088 from Santa Cruz Biotechnology
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UIP1 shRNA Plasmid (h) - sc-91088-SH from Santa Cruz Biotechnology
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UIP1 shRNA (h) Lentiviral Particles - sc-91088-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU127701 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9886 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9886 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00908 from Sigma-Aldrich
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HAUS7 siRNA (Human) - CRJ0740 from Cohesion Biosciences
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HAUS7 - MBS829882 from MyBioSource
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HAUS7 shRNA Plasmid (Human) - CHJ0740 from Cohesion Biosciences
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HAUS7 miRNA 3'UTR clone - MiUTR3H-02828 from Creative biogene
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