| Gene Symbol |
SEC31B
|
| Entrez Gene |
25956
|
| Alt Symbol |
SEC31B-1, SEC31L2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
SEC31 homolog B (S. cerevisiae)
|
| Other Description |
SEC31-like 2|SEC31-like protein 2|SEC31-related protein B|protein transport protein Sec31B|secretory pathway component Sec31B-1
|
| Swissprots |
B7ZM75 Q9NQW1 Q86UF0 Q9Y4Q8 Q6MZS3
|
| Accessions |
EAW49821 EAW49822 EAW49823 EAW49824 Q9NQW1 AF274863 AAF78243 AF279139 AK093637 AK098002 AK128343 AK289975 BAF82664 AK294551 BAG57754 AL080141 CAB45735 BC034946 AAH34946 BC044569 BC053949 BC071580 BC144312 BC144313 AAI44314 BC148657 AAI48658 BM719543 BX640914 CAE45955 NM_015490 NP_056305 NM_198138
|
| Function |
As a component of the coat protein complex II (COPII), may function in vesicle budding and cargo export from the endoplasmic reticulum. {ECO:0000269|PubMed:16495487}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:16495487}. Cytoplasmic vesicle, COPII-coated vesicle membrane {ECO:0000269|PubMed:16495487}; Peripheral membrane protein {ECO:0000269|PubMed:16495487}; Cytoplasmic side {ECO:0000269|PubMed:16495487}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:16495487}; Peripheral membrane protein {ECO:0000269|PubMed:16495487}.
|
| Tissue Specificity |
Ubiquitously expressed at low levels with specific expression in thymus and testis. Expressed in testis by Sertoli cells, Leydig cells and spermatogonia and in cerebellum more prominently by Purkinje and granular cells (at protein level). {ECO:0000269|PubMed:10788476, ECO:0000269|PubMed:16495487}.
|
| Top Pathways |
Protein processing in endoplasmic reticulum
|