Gene Symbol | CACNG1 |
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Entrez Gene | 786 |
Alt Symbol | CACNLG |
Species | Human |
Gene Type | protein-coding |
Description | calcium channel, voltage-dependent, gamma subunit 1 |
Other Description | L-type calcium channel gamma polypeptide|dihydropyridine-sensitive L-type, skeletal muscle calcium channel subunit gamma|neuronal dihydropyridine-sensitive calcium channel gamma subunit|voltage-dependent calcium channel gamma-1 subunit |
Swissprots | Q06432 Q14D59 B2R9N3 |
Accessions | CAA79671 CAB62573 EAW89022 Q06432 AF086300 AK313852 BAG36580 BC069493 AAH69493 BC113486 AAI13487 BC113492 AAI13493 DA898357 HQ258641 ADR83392 L07738 AAA51904 NM_000727 NP_000718 |
Function | This protein is a subunit of the dihydropyridine (DHP) sensitive calcium channel. Plays a role in excitation-contraction coupling. The skeletal muscle DHP-sensitive Ca(2+) channel may function only as a multiple subunit complex. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Skeletal muscle. |
Top Pathways | MAPK signaling pathway, Cardiac muscle contraction, Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy |
L-type Ca ++ CP γ1 CRISPR/Cas9 KO Plasmid (h) - sc-406667 from Santa Cruz Biotechnology
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L-type Ca ++ CP γ1 HDR Plasmid (h) - sc-406667-HDR from Santa Cruz Biotechnology
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L-type Ca ++ CP γ1 Double Nickase Plasmid (h) - sc-406667-NIC from Santa Cruz Biotechnology
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L-type Ca ++ CP γ1 Double Nickase Plasmid (h2) - sc-406667-NIC-2 from Santa Cruz Biotechnology
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L-type Ca ++ CP γ1 CRISPR Activation Plasmid (h) - sc-406667-ACT from Santa Cruz Biotechnology
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L-type Ca ++ CP γ1 CRISPR Activation Plasmid (h2) - sc-406667-ACT-2 from Santa Cruz Biotechnology
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L-type Ca ++ CP γ1 Lentiviral Activation Particles (h) - sc-406667-LAC from Santa Cruz Biotechnology
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L-type Ca ++ CP γ1 Lentiviral Activation Particles (h2) - sc-406667-LAC-2 from Santa Cruz Biotechnology
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L-type Ca ++ CP γ1 siRNA (h) - sc-93870 from Santa Cruz Biotechnology
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L-type Ca ++ CP γ1 shRNA Plasmid (h) - sc-93870-SH from Santa Cruz Biotechnology
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L-type Ca ++ CP γ1 shRNA (h) Lentiviral Particles - sc-93870-V from Santa Cruz Biotechnology
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CACNG1 RNAi - H00000786-R01 from Novus Biologicals
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MISSION® esiRNA - EHU007931 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5273 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5273 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04951 from Sigma-Aldrich
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CACNG1 siRNA (Human) - CRH0551 from Cohesion Biosciences
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CACNG1 - MBS8216090 from MyBioSource
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shRNA set against Human CACNG1 (NM_000727.3) - SHH253465 from Creative biogene
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Human CACNG1 siRNA - orb261053 from Biorbyt
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CACNG1 shRNA Plasmid (Human) - CHH0551 from Cohesion Biosciences
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