TMOD1

Gene Symbol TMOD1
Entrez Gene 7111
Alt Symbol D9S57E, ETMOD, TMOD
Species Human
Gene Type protein-coding
Description tropomodulin 1
Other Description E-Tmod|e-tropomodulin|erythrocyte tropomodulin|tropomodulin-1
Swissprots B2RB77 P28289 Q9BUF1 Q5T7W3
Accessions AAG30124 EAW58845 EAW58846 P28289 AF131836 AK095748 BAG53119 AK096156 AK314533 BAG37124 BC002660 AAH02660 BU783086 DA015088 DQ893027 ABM83953 DQ896271 ABM87270 M77016 AAA61224 NM_001166116 NP_001159588 NM_003275 NP_003266
Function Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus. {ECO:0000269|PubMed:8002995}.
Subcellular Location Cytoplasm, cytoskeleton. Note=In myofibrils with sarcomeric structure, localizes to the pointed end of actin thin filaments (PubMed:25250574). {ECO:0000269|PubMed:25250574}.
Tissue Specificity Highly expressed in the erythrocyte, heart and skeletal muscle.

tropomodulin 1 CRISPR/Cas9 KO Plasmid (h) - sc-406485 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

tropomodulin 1 HDR Plasmid (h) - sc-406485-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

tropomodulin 1 Double Nickase Plasmid (h) - sc-406485-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

tropomodulin 1 Double Nickase Plasmid (h2) - sc-406485-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

tropomodulin 1 CRISPR Activation Plasmid (h) - sc-406485-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

tropomodulin 1 CRISPR Activation Plasmid (h2) - sc-406485-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

tropomodulin 1 Lentiviral Activation Particles (h) - sc-406485-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

tropomodulin 1 Lentiviral Activation Particles (h2) - sc-406485-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

tropomodulin 1 siRNA (h) - sc-92724 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

tropomodulin 1 shRNA Plasmid (h) - sc-92724-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

tropomodulin 1 shRNA (h) Lentiviral Particles - sc-92724-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN21696 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21696 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR09721 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr09721

TMOD1 siRNA (Human) - CRH4878 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Tropomodulin 1 RNAi - H00007111-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

TMOD1 - MBS8230841 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Human TMOD1 siRNA - orb265380 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TMOD1 shRNA Plasmid (Human) - CHH4878 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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