Gene Symbol |
CAND2
|
Entrez Gene |
23066
|
Alt Symbol |
TIP120B, Tp120b
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
cullin-associated and neddylation-dissociated 2 (putative)
|
Other Description |
TBP interacting protein|TBP-interacting protein 120B|TBP-interacting protein of 120 kDa B|cullin-associated NEDD8-dissociated protein 2|cullin-associated and neddylation-dissociated protein 2|epididymis tissue protein Li 169|p120 CAND2
|
Swissprots |
E9KL24 B9EGM9 O75155
|
Accessions |
EAW64143 O75155 AB014567 BAA31642 BC136592 AAI36593 BE256308 BX502783 BX648800 DB471722 DR001490 GU727621 ADU87623 W44800 XM_011533503 XP_011531805 XM_011533504 XP_011531806 NM_001162499 NP_001155971 NM_012298 NP_036430
|
Function |
Probable assembly factor of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate-recognition F-box subunit in SCF complexes, thereby playing a key role in the cellular repertoire of SCF complexes. {ECO:0000250}.
|
Subcellular Location |
Nucleus {ECO:0000250}.
|
Tissue Specificity |
Expressed in epididymis (at protein level). {ECO:0000269|PubMed:20736409}.
|