Gene Symbol | RAB6C |
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Entrez Gene | 84084 |
Alt Symbol | WTH3 |
Species | Human |
Gene Type | protein-coding |
Description | RAB6C, member RAS oncogene family |
Other Description | rab6-like protein WTH3|ras-related protein Rab-6C |
Swissprots | Q6FIF7 Q53RU3 Q9H0N0 Q9P128 |
Accessions | AAF28422 AAY15045 EAW95362 EAX11700 Q9H0N0 AF309646 AAN39685 AK055504 AL136727 CAB66661 BC120998 BC120999 AAI21000 CR533469 CAG38500 NM_032144 NP_115520 |
Function | May be involved in the regulation of centrosome duplication and cell cycle progression. {ECO:0000269|PubMed:17426708, ECO:0000269|PubMed:18992151, ECO:0000269|PubMed:20064528}. |
Subcellular Location | Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. |
Tissue Specificity | Highest levels are found in fetal and adult brain, prostate, testis and spinal cord. Undetectable expression in adrenal gland, skeletal muscle, bone marrow, fetal, and adult liver, heart, salivary gland, and trachea. Detected in the HEK293, HEK293T, LNCaP, MCF-7, T-47D and EVSA-T cell lines (at protein level). {ECO:0000269|PubMed:20064528}. |
Rab 6C CRISPR/Cas9 KO Plasmid (h) - sc-417512 from Santa Cruz Biotechnology
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Rab 6C HDR Plasmid (h) - sc-417512-HDR from Santa Cruz Biotechnology
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Rab 6C Double Nickase Plasmid (h) - sc-417512-NIC from Santa Cruz Biotechnology
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Rab 6C Double Nickase Plasmid (h2) - sc-417512-NIC-2 from Santa Cruz Biotechnology
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Rab 6 CRISPR Activation Plasmid (h) - sc-417512-ACT from Santa Cruz Biotechnology
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Rab 6C CRISPR Activation Plasmid (h2) - sc-417512-ACT-2 from Santa Cruz Biotechnology
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Rab 6C Lentiviral Activation Particles (h) - sc-417512-LAC from Santa Cruz Biotechnology
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Rab 6C Lentiviral Activation Particles (h2) - sc-417512-LAC-2 from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN17864 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17864 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10608 from Sigma-Aldrich
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RAB6C siRNA (Human) - CRJ3296 from Cohesion Biosciences
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RAB6C RNAi - H00084084-R01 from Novus Biologicals
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RAB6C - MBS8207462 from MyBioSource
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shRNA set against Human Rab6 (NM_032144.2) - SHH388524 from Creative biogene
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shRNA set against Human RAB6C(NM_032144.2) - SHR160122 from Creative biogene
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RAB6C shRNA Plasmid (Human) - CHJ3296 from Cohesion Biosciences
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RAB6C miRNA 3'UTR clone - MiUTR1H-08574 from Creative biogene
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