| Gene Symbol |
ELMOD3
|
| Entrez Gene |
84173
|
| Alt Symbol |
DFNB88, LST3, RBED1, RBM29
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ELMO/CED-12 domain containing 3
|
| Other Description |
C330008I15Rik|ELMO domain-containing protein 3|RNA binding motif and ELMO domain 1|RNA binding motif and ELMO/CED-12 domain 1|RNA binding motif protein 29|RNA-binding motif and ELMO domain-containing protein 1|RNA-binding motif protein 29|RNA-binding protein 29|deafness, autosomal recessive 88|liver-specific organic anion transporter 3TM12|organic anion transporter LST-3b
|
| Swissprots |
Q8WV70 Q8TCK4 Q2M1K3 Q2XSU4 D6W5K4 Q2XSU3 Q9H6Q8 Q8WY75 Q96FG2 B8ZZD6 Q8NAC1
|
| Accessions |
AAY24127 EAW99521 EAW99522 EAW99523 EAW99524 EAW99525 EAW99526 EAW99527 EAW99528 EAW99529 Q96FG2 AF258573 AAG23776 AK092920 AK307252 AL713718 CAD28512 BC001942 AAH01942 BC010991 AAH10991 BC018666 AAH18666 BC054504 BC112324 AAI12325 DA294897 DQ256726 ABB69067 DQ256727 ABB69068 EB385493 HQ447762 ADQ32247 XM_005264596 XP_005264653 XM_005264597 XP_005264654 XM_005264598 XP_005264655 XM_006712116 XP_006712179 XR_426997 NM_001135021 NP_001128493 NM_001135022 NP_001128494 NM_001135023 NP_001128495 NM_032213 NP_115589
|
| Function |
Acts as a GTPase-activating protein (GAP) for ARL2 with low specific activity. {ECO:0000269|PubMed:24039609}.
|
| Subcellular Location |
Cell projection, stereocilium {ECO:0000269|PubMed:24039609}. Cell projection, kinocilium {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:24039609}. Note=Also present in the cuticular plate of auditory hair cells. Expressed along the length of the stereocilia, but excluded from the very tip (By similarity). Colocalizes with F-actin cytoskeleton. {ECO:0000250}.
|
| Tissue Specificity |
Both isoform 1 and isoform 6 are widely expressed. {ECO:0000269|PubMed:24039609}.
|