| Gene Symbol |
SULT1C4
|
| Entrez Gene |
27233
|
| Alt Symbol |
SULT1C, SULT1C2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
sulfotransferase family, cytosolic, 1C, member 4
|
| Other Description |
ST1C4|SULT1C#2|sulfotransferase 1C2|sulfotransferase 1C4|sulfotransferase family, cytosolic, 1C, member 2|sulfotransferase family, cytosolic, 1C, member C2
|
| Swissprots |
Q069I8 Q53S63 Q08AS5 O75897
|
| Accessions |
AAF72810 AAY14742 ABI75348 EAW53885 EAW53886 O75897 AK297851 BAG60183 AK298755 BAG60897 BC058861 AAH58861 BC125043 AAI25044 XM_005263919 XP_005263976 NM_006588 NP_006579
|
| Function |
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of drugs, xenobiotic compounds, hormones, and neurotransmitters. May be involved in the activation of carcinogenic hyroxylamines. Shows activity towards p-nitrophenol and N-hydroxy-2-acetylamino-fluorene (N-OH-2AAF). {ECO:0000269|PubMed:17425406}.
|
| Subcellular Location |
Cytoplasm.
|
| Tissue Specificity |
Expressed at high levels in fetal lung and kidney and at low levels in fetal heart, adult kidney, ovary and spinal chord.
|