| Gene Symbol |
XPNPEP1
|
| Entrez Gene |
7511
|
| Alt Symbol |
APP1, SAMP, XPNPEP, XPNPEPL, XPNPEPL1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
|
| Other Description |
X-Pro aminopeptidase 1|X-prolyl aminopeptidase 1, soluble|aminoacylproline aminopeptidase|aminopeptidase P, cytosolic|cytosolic aminopeptidase P|soluble aminopeptidase P|xaa-Pro aminopeptidase 1
|
| Swissprots |
Q53EX6 G5E9Y2 O15250 Q8N3Q0 Q9NQW7 A8K071 Q96D23 G8JLB2
|
| Accessions |
EAW49576 EAW49577 Q9NQW7 AF195530 AAF97866 AF272981 AAF75795 AK093693 BAG52749 AK094900 AK095447 AK223513 BAD97233 AK289436 BAF82125 AK295756 BAG58586 AK304367 BAG65206 AL833411 CAD38640 BC005126 AAH05126 BC007579 AAH07579 BC013417 AAH13417 BX537682 CAH18706 CR456922 CAG33203 DA484161 EU176414 ABW03865 EU176811 ABW03612 X95762 CAA65068 XM_011540129 XP_011538431 XM_011540130 XP_011538432 XM_011540131 XP_011538433 XM_011540132 XP_011538434 XM_011540133 XP_011538435 XM_011540134 XP_011538436 XM_011540135 XP_011538437 XM_011540136 XP_011538438 XM_011540137 XP_011538439 XM_011540138 XP_011538440 XR_945811 NM_001167604 NP_001161076 NM_020383 NP_065116 NR_030724
|
| Function |
Contributes to the degradation of bradykinin. Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro.
|
| Subcellular Location |
Cytoplasm {ECO:0000250}.
|
| Tissue Specificity |
Expressed in all tissues tested, including pancreas, heart, muscle, kidney, liver, lung and brain. Highest levels in pancreas. {ECO:0000269|PubMed:9465902}.
|