| Gene Symbol |
HIST1H2BD
|
| Entrez Gene |
3017
|
| Alt Symbol |
H2B.1B, H2B/b, H2BFB, HIRIP2, dJ221C16.6
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
histone cluster 1, H2bd
|
| Other Description |
H2B histone family, member B|HIRA-interacting protein 2|histone 1, H2bd|histone H2B type 1-D|histone H2B.1 B|histone H2B.b
|
| Swissprots |
P58876
|
| Accessions |
AAA63190 AAN06687 EAW55535 EAW55536 P58876 AJ223353 CAA11277 AK292712 BAF85401 BC002842 AAH02842 BC096122 AAH96122 BE245851 BM153714 XM_005249039 XP_005249096 NM_021063 NP_066407 NM_138720 NP_619790
|
| Function |
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
|
| Subcellular Location |
Nucleus. Chromosome.
|
| Top Pathways |
Systemic lupus erythematosus, Viral carcinogenesis, Alcoholism
|