Gene Symbol | CCL19 |
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Entrez Gene | 6363 |
Alt Symbol | CKb11, ELC, MIP-3b, MIP3B, SCYA19 |
Species | Human |
Gene Type | protein-coding |
Description | chemokine (C-C motif) ligand 19 |
Other Description | C-C motif chemokine 19|CC chemokine ligand 19|CK beta-11|EBI1 ligand chemokine|EBI1-ligand chemokine|MIP-3-beta|beta chemokine exodus-3|beta-chemokine exodus-3|epstein-Barr virus-induced molecule 1 ligand chemokine|exodus-3|macrophage inflammatory protein 3 beta|macrophage inflammatory protein 3-beta|small inducible cytokine subfamily A (Cys-Cys), member 19|small-inducible cytokine A19 |
Swissprots | O00697 O00736 Q99731 |
Accessions | ABK41949 CAA11307 EAW58416 Q99731 AB000887 BAA20383 AK311945 BAG34886 AX772806 CAE06252 BC027968 AAH27968 CR456868 CAG33149 DQ895236 ABM86162 EU176240 ABW03691 U77180 AAC50944 U88321 AAC23905 NM_006274 NP_006265 |
Function | May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. {ECO:0000269|PubMed:9498785}. |
Subcellular Location | Secreted. |
Tissue Specificity | Expressed at high levels in the lymph nodes, thymus and appendix. Intermediate levels seen in colon and trachea, while low levels found in spleen, small intestine, lung, kidney and stomach. |
Top Pathways | Cytokine-cytokine receptor interaction, Chemokine signaling pathway |
MIP3b (CCL19) Human ELISA kit - ab100601 from Abcam
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Rat CCL19 / MIP3-Beta ELISA Kit (Sandwich ELISA) - LS-F5524 from LifeSpan Bioscience
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Human CCL19 / MIP3-Beta ELISA Kit (Sandwich ELISA) - LS-F2510 from LifeSpan Bioscience
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Human CCL19 / MIP3-Beta ELISA Kit (Sandwich ELISA) - LS-F4958 from LifeSpan Bioscience
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Mouse CCL19 / MIP3-Beta ELISA Kit (Sandwich ELISA) - LS-F4959 from LifeSpan Bioscience
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Dog CCL19 / MIP3-Beta ELISA Kit (Sandwich ELISA) - LS-F6160 from LifeSpan Bioscience
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Human CCL19 / MIP3-Beta ELISA Kit (Sandwich ELISA) - LS-F1004 from LifeSpan Bioscience
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Human CCL19 / MIP3-Beta ELISA Kit (Sandwich ELISA) - LS-F11052 from LifeSpan Bioscience
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Human MIP-3 β / CCL19 ELISA Kit - RAB0052 from Sigma-Aldrich
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CCL19/MIP-3 beta BioAssay ELISA Kit, Human - 143748 from USBiological Life Science
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Human CCL19/MIP-3 beta Biotin Fluorokine Flow Cytometry Kit - NFCCL19 from R&D Systems
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Mouse CCL19/MIP-3 beta DuoSet ELISA - DY440 from R&D Systems
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Human CCL19/MIP-3 beta DuoSet ELISA - DY361 from R&D Systems
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Human MIP3b ELISA kit - 55R-2066 from Fitzgerald
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Mouse MIP3b ELISA kit - 55R-2092 from Fitzgerald
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MIP-3β ELISA Kit (Human) : 96 Wells (OKAG00155) - OKAG00155 from Aviva Systems Biology
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Human CCL19 ELISA Kit - orb219252 from Biorbyt
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Human CCL19 ELISA Kit - abx056038 from Abbexa
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Human MIP3b ELISA Kit - abx152340 from Abbexa
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C-C motif chemokine 19, CCL19, Human, ELISA Kit - E0096h from ARP American Research Products
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CCL19/MIP-3 beta, Human, ELISA Kit - PB-0456 from ARP American Research Products
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Macrophage Inflammatory Protein 3 Beta (MIP3b), Human, ELISA Kit - SEA096Hu from ARP American Research Products
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Macrophage Inflammatory Protein-3a, MIP-3a, Human, ELISA Kit - CSB-E04670h from ARP American Research Products
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Macrophage Inflammatory Protein 3b, MIP-3b/ELC/CCL19, Human, ELISA Kit - E-EL-H1528 from ARP American Research Products
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Macrophage Inflammatory Protein 3b, MIP-3b, Mouse, ELISA Kit - E-EL-M0769 from ARP American Research Products
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