| Gene Symbol |
TNP1
|
| Entrez Gene |
7141
|
| Alt Symbol |
TP1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
transition protein 1 (during histone to protamine replacement)
|
| Other Description |
STP-1|TP-1|spermatid nuclear transition protein 1
|
| Swissprots |
P09430
|
| Accessions |
AAA61202 AAX88913 BAF36709 CBH19478 CBH30623 EAW70577 P09430 BC029516 AAH29516 HQ448184 ADQ32665 X07948 CAA30774 NM_003284 NP_003275
|
| Function |
In the elongating spermatids of mammals, the conversion of nucleosomal chromatin to the compact, non-nucleosomal form found in the sperm nucleus is associated with the appearance of a small set of basic chromosomal transition proteins.
|
| Subcellular Location |
Nucleus. Chromosome.
|
| Tissue Specificity |
Expressed by spermatids (at protein level). {ECO:0000269|PubMed:9809674}.
|
![Western Blot: TNP1 Overexpression Lysate (Adult Normal) [NBP2-08023] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for TNP1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/5869_TNP1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-08023-img0001.jpg)