Gene Symbol | KIF26B |
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Entrez Gene | 55083 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | kinesin family member 26B |
Other Description | kinesin-like protein KIF26B |
Swissprots | Q8IVR1 Q9NWB4 Q2KJY2 Q6ZQR9 Q8IUN3 Q6ZUZ0 |
Accessions | EAW77136 Q2KJY2 AK001019 BAA91469 AK095500 AK125187 BAC86076 AK128806 BAC87614 AK293964 BAG57336 AK297303 BAG59771 AY923834 AAY17361 BC035896 AAH35896 BC042481 AAH42481 XM_011544214 XP_011542516 XM_011544215 XP_011542517 XM_011544216 XP_011542518 XM_011544217 XP_011542519 XM_011544218 XP_011542520 NM_018012 NP_060482 |
Function | Essential for embryonic kidney development. Plays an important role in the compact adhesion between mesenchymal cells adjacent to the ureteric buds, possibly by interacting with MYH10. This could lead to the establishment of the basolateral integrity of the mesenchyme and the polarized expression of ITGA8, which maintains the GDNF expression required for further ureteric bud attraction. Although it seems to lack ATPase activity it is constitutively associated with microtubules (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000305}. |
KIF26B CRISPR/Cas9 KO Plasmid (h) - sc-407359 from Santa Cruz Biotechnology
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KIF26B HDR Plasmid (h) - sc-407359-HDR from Santa Cruz Biotechnology
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KIF26B Double Nickase Plasmid (h) - sc-407359-NIC from Santa Cruz Biotechnology
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KIF26B Double Nickase Plasmid (h2) - sc-407359-NIC-2 from Santa Cruz Biotechnology
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KIF26B CRISPR Activation Plasmid (h) - sc-407359-ACT from Santa Cruz Biotechnology
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KIF26B CRISPR Activation Plasmid (h2) - sc-407359-ACT-2 from Santa Cruz Biotechnology
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KIF26B Lentiviral Activation Particles (h) - sc-407359-LAC from Santa Cruz Biotechnology
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KIF26B Lentiviral Activation Particles (h2) - sc-407359-LAC-2 from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU025281 from Sigma-Aldrich
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MISSION® esiRNA - EHU050701 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN11194 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11194 from Sigma-Aldrich
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KIF26B siRNA (Human) - CRJ0455 from Cohesion Biosciences
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shRNA set against Human KIF26B (NM_018012.3) - SHH325223 from Creative biogene
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Human KIF26B siRNA - orb270956 from Biorbyt
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KIF26B shRNA Plasmid (Human) - CHJ0455 from Cohesion Biosciences
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KIF26B miRNA 3'UTR clone - MiUTR1H-05310 from Creative biogene
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