Gene Symbol | LIPT2 |
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Entrez Gene | 387787 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | lipoyl(octanoyl) transferase 2 (putative) |
Other Description | lipoate-protein ligase B|lipoyl/octanoyl transferase|octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase|putative lipoyltransferase 2, mitochondrial|putative octanoyltransferase, mitochondrial |
Swissprots | A6NK58 |
Accessions | A6NK58 EAW74939 CN348282 CX752266 XM_011545021 XP_011543323 NM_001144869 NP_001138341 |
Function | Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity). {ECO:0000250}. |
Subcellular Location | Mitochondrion {ECO:0000305}. |
Top Pathways | Lipoic acid metabolism |
LIPT2 CRISPR/Cas9 KO Plasmid (h) - sc-415754 from Santa Cruz Biotechnology
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LIPT2 HDR Plasmid (h) - sc-415754-HDR from Santa Cruz Biotechnology
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LIPT2 Double Nickase Plasmid (h) - sc-415754-NIC from Santa Cruz Biotechnology
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LIPT2 Double Nickase Plasmid (h2) - sc-415754-NIC-2 from Santa Cruz Biotechnology
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LIPT2 CRISPR Activation Plasmid (h) - sc-415754-ACT from Santa Cruz Biotechnology
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LIPT2 CRISPR Activation Plasmid (h2) - sc-415754-ACT-2 from Santa Cruz Biotechnology
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LIPT2 Lentiviral Activation Particles (h) - sc-415754-LAC from Santa Cruz Biotechnology
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LIPT2 Lentiviral Activation Particles (h2) - sc-415754-LAC-2 from Santa Cruz Biotechnology
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LIPT2 siRNA (h) - sc-105659 from Santa Cruz Biotechnology
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LIPT2 shRNA Plasmid (h) - sc-105659-SH from Santa Cruz Biotechnology
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LIPT2 shRNA (h) Lentiviral Particles - sc-105659-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN11752 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11752 from Sigma-Aldrich
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LIPT2 siRNA (Human) - CRJ7759 from Cohesion Biosciences
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shRNA set against Human LIPT2 (NM_001144869.1) - SHH330771 from Creative biogene
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Human LIPT2 siRNA - orb278260 from Biorbyt
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LIPT2 shRNA Plasmid (Human) - CHJ7759 from Cohesion Biosciences
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LIPT2 miRNA 3'UTR clone - MiUTR3H-15316 from Creative biogene
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