Gene Symbol | SLC25A10 |
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Entrez Gene | 1468 |
Alt Symbol | DIC |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 |
Other Description | dicarboxylate ion carrier|mitochondrial dicarboxylate carrier |
Swissprots | Q9UBX3 Q542Z3 Q96BA1 Q96IP1 |
Accessions | CAB60007 CAF86566 EAW89681 EAW89682 Q9UBX3 AI081980 AJ131613 CAB59892 AK075249 BAC11497 AK303808 BAG64761 BC007355 AAH07355 BC015797 AAH15797 BM561945 DQ893263 ABM84189 DQ896592 ABM87591 HY259124 XM_005257074 XP_005257131 NM_001270888 NP_001257817 NM_001270953 NP_001257882 NM_012140 NP_036272 |
Function | Involved in translocation of malonate, malate and succinate in exchange for phosphate, sulfate, sulfite or thiosulfate across mitochondrial inner membrane. |
Subcellular Location | Mitochondrion inner membrane; Multi-pass membrane protein. |
Tissue Specificity | Present in high amounts in liver and kidney, and at lower levels in all the other tissues analyzed. {ECO:0000269|PubMed:10585886}. |
Top Pathways | Proximal tubule bicarbonate reclamation |
DIC CRISPR/Cas9 KO Plasmid (h) - sc-417651 from Santa Cruz Biotechnology
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DIC HDR Plasmid (h) - sc-417651-HDR from Santa Cruz Biotechnology
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DIC Double Nickase Plasmid (h) - sc-417651-NIC from Santa Cruz Biotechnology
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DIC Double Nickase Plasmid (h2) - sc-417651-NIC-2 from Santa Cruz Biotechnology
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DIC CRISPR Activation Plasmid (h) - sc-417651-ACT from Santa Cruz Biotechnology
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DIC CRISPR Activation Plasmid (h2) - sc-417651-ACT-2 from Santa Cruz Biotechnology
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DIC Lentiviral Activation Particles (h) - sc-417651-LAC from Santa Cruz Biotechnology
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DIC Lentiviral Activation Particles (h2) - sc-417651-LAC-2 from Santa Cruz Biotechnology
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DIC siRNA (h) - sc-93937 from Santa Cruz Biotechnology
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DIC shRNA Plasmid (h) - sc-93937-SH from Santa Cruz Biotechnology
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DIC shRNA (h) Lentiviral Particles - sc-93937-V from Santa Cruz Biotechnology
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SLC25A10 RNAi - H00001468-R01 from Novus Biologicals
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MISSION® esiRNA - EHU080881 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19484 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19484 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR12406 from Sigma-Aldrich
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SLC25A10 siRNA (Human) - CRH1036 from Cohesion Biosciences
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SLC25A10 - MBS8227589 from MyBioSource
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shRNA set against Human SLC25A10 (NM_012140.4) - SHH409392 from Creative biogene
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Human SLC25A10 siRNA - orb261538 from Biorbyt
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SLC25A10 shRNA Plasmid (Human) - CHH1036 from Cohesion Biosciences
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SLC25A10 miRNA 3'UTR clone - MiUTR3H-08718 from Creative biogene
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