Gene Symbol |
BLCAP
|
Entrez Gene |
10904
|
Alt Symbol |
BC10
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
bladder cancer associated protein
|
Other Description |
bladder cancer 10 kDa protein|bladder cancer related protein (10kD)|bladder cancer-associated protein
|
Swissprots |
P62952 A2A2K7
|
Accessions |
EAW76056 P62952 AA780553 AF053470 AAC06370 AI920860 AK074498 AK124822 AL049288 BC047692 AAH47692 BC071704 AAH71704 BP293276 CB155706 DA198124 DA262965 DA632207 DA943717 NM_001167820 NP_001161292 NM_001167821 NP_001161293 NM_001167822 NP_001161294 NM_001167823 NP_001161295 NM_006698 NP_006689
|
Function |
May regulate cell proliferation and coordinate apoptosis and cell cycle progression via a novel mechanism independent of both p53/TP53 and NF-kappa-B. {ECO:0000269|PubMed:17031575}.
|
Subcellular Location |
Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
|
Tissue Specificity |
Ubiquitous. Expressed in cervical tissues. Down-regulated in bladder invasive carcinoma, renal cell carcinoma and in primary cervical carcinoma. {ECO:0000269|PubMed:10197429, ECO:0000269|PubMed:16675915, ECO:0000269|PubMed:19908260}.
|