VPS13B
| Gene Symbol | VPS13B |
|---|---|
| Entrez Gene | 157680 |
| Alt Symbol | CHS1, COH1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | vacuolar protein sorting 13 homolog B (yeast) |
| Other Description | vacuolar protein sorting-associated protein 13B |
| Swissprots | Q9NWV1 Q7Z7G4 Q7Z7G8 Q709C7 Q8NB77 Q7Z7G5 Q7Z7G7 Q709C6 Q7Z7G6 Q9Y4E7 C9JD30 |
| Accessions | CCQ43856 EAW91786 EAW91787 EAW91788 Q7Z7G8 AB011104 BAA25458 AJ608772 CAE75584 AJ608773 CAE75585 AK000590 BAA91275 AK091431 BAC03664 AK223122 BAD96842 AY223814 AAP41102 AY223815 AAP41103 AY223816 AAP41104 AY223817 AAP41105 AY223818 AAP41106 BC020813 AAH20813 BC033121 AAH33121 BC094749 BC132976 BC132978 BC144379 BX098890 BX647561 BX648610 CA447487 XM_005250800 XP_005250857 XM_005250801 XP_005250858 XM_006716510 XP_006716573 XM_006716511 XP_006716574 XM_011516848 XP_011515150 XM_011516849 XP_011515151 XM_011516850 XP_011515152 XM_011516851 XP_011515153 XM_011516852 XP_011515154 XM_011516853 XP_011515155 XM_011516854 XP_011515156 XM_011516855 XP_011515157 XM_011516856 XP_011515158 XM_011516857 XP_011515159 XM_011516858 XP_011515160 XM_011516859 XP_011515161 XM_011516860 XP_011515162 XM_011516861 XP_011515163 XM_011516862 XP_011515164 XM_011516863 XP_011515165 XM_011516864 XP_011515166 XM_011516865 XP_011515167 XM_011516866 XP_011515168 XR_928301 XR_928302 XR_928303 XR_928304 NM_015243 NP_056058 NM_017890 NP_060360 NM_152564 NP_689777 NM_181661 NP_858047 NR_047582 NM_184042 |
| Function | May be involved in protein sorting in post Golgi membrane traffic. {ECO:0000250}. |
| Tissue Specificity | Widely expressed. There is apparent differential expression of different transcripts. In fetal brain, lung, liver, and kidney, two transcripts of 2 and 5 kb are identified. These transcripts are also seen in all adult tissues analyzed. A larger transcript (12-14 kb) is expressed in prostate, testis, ovary, and colon in the adult. Expression is very low in adult brain tissue. Isoform 1 and isoform 2 are expressed in brain and retina. Isoform 2 is expressed ubiquitously. {ECO:0000269|PubMed:12730828, ECO:0000269|PubMed:19006247}. |
COH1 CRISPR/Cas9 KO Plasmid (h) - sc-414768 from Santa Cruz Biotechnology
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COH1 HDR Plasmid (h) - sc-414768-HDR from Santa Cruz Biotechnology
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COH1 Double Nickase Plasmid (h) - sc-414768-NIC from Santa Cruz Biotechnology
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COH1 Double Nickase Plasmid (h2) - sc-414768-NIC-2 from Santa Cruz Biotechnology
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COH1 CRISPR Activation Plasmid (h) - sc-414768-ACT from Santa Cruz Biotechnology
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COH1 CRISPR Activation Plasmid (h2) - sc-414768-ACT-2 from Santa Cruz Biotechnology
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COH1 Lentiviral Activation Particles (h) - sc-414768-LAC from Santa Cruz Biotechnology
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COH1 Lentiviral Activation Particles (h2) - sc-414768-LAC-2 from Santa Cruz Biotechnology
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COH1 siRNA (h) - sc-105225 from Santa Cruz Biotechnology
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COH1 shRNA Plasmid (h) - sc-105225-SH from Santa Cruz Biotechnology
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COH1 shRNA (h) Lentiviral Particles - sc-105225-V from Santa Cruz Biotechnology
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VPS13B RNAi - H00157680-R02 from Novus Biologicals
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VPS13B RNAi - H00157680-R05 from Novus Biologicals
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VPS13B RNAi - H00157680-R03 from Novus Biologicals
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MISSION® esiRNA - EHU086001 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2432 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2432 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10723 from Sigma-Aldrich
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VPS13B siRNA (Human) - CRJ5829 from Cohesion Biosciences
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VPS13B RNAi - H00157680-R01 from Novus Biologicals
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VPS13B RNAi - H00157680-R04 from Novus Biologicals
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VPS13B - MBS8220008 from MyBioSource
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shRNA set against Human VPS13B (NM_181661.2) - SHH444796 from Creative biogene
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shRNA set against Human VPS13B(NM_015243.2) - SHL126972 from Creative biogene
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shRNA set against Human VPS13B(NM_181661.2) - SHL126990 from Creative biogene
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