Gene Symbol | FUT1 |
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Entrez Gene | 2523 |
Alt Symbol | H, HH, HSC |
Species | Human |
Gene Type | protein-coding |
Description | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
Other Description | 2-alpha-L-fucosyltransferase|GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 1|alpha (1,2) fucosyltransferase|alpha(1,2) fucosyltransferase 1|alpha(1,2)FT 1|blood group H alpha 2-fucosyltransferase|fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase)|galactoside 2-alpha-L-fucosyltransferase 1 |
Swissprots | O14506 O14505 O14507 P19526 |
Accessions | AAL57863 AAT42242 AAV51818 AAW82437 AAY96648 AAZ81507 ABC59307 ABU75130 ABU75131 ABU75132 ACN41952 ACT82507 ADP20182 ADX86835 AEA76422 AFO67890 AFS30924 AGU16805 AGY31283 AHJ09661 AII25874 AIT68783 AIU94775 AIU94776 BAA20556 BAA20557 BAA20558 BAA20559 BAA20560 BAA28952 CAA93435 CAC81751 CAQ56300 CAQ81977 EAW52399 P19526 BC074732 AAH74732 CN359119 D87935 D87936 D87937 D87938 D87939 D87940 D87941 M35531 AAA52639 XM_006723127 XP_006723190 NM_000148 NP_000139 |
Function | Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble A and B antigen synthesis pathway. H and Se enzymes fucosylate the same acceptor substrates but exhibit different Km values. |
Subcellular Location | Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi. |
Top Pathways | Glycosphingolipid biosynthesis - globo series, Glycosphingolipid biosynthesis - lacto and neolacto series |
FucT-l (97-I) - sc-52398 from Santa Cruz Biotechnology
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Anti-Galactoside 2-alpha-L-fucosyltransferase 1 antibody - ab198712 from Abcam
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Anti-FUT1 / HSC Antibody (aa287-336) - LS-C116259 from LifeSpan Bioscience
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Anti-FUT1 / HSC Antibody (aa164-195) - LS-C99304 from LifeSpan Bioscience
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Anti-FUT1 / HSC Antibody (aa106-119) - LS-C139808 from LifeSpan Bioscience
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Anti-FUT1 / HSC Antibody - LS-C310411 from LifeSpan Bioscience
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Anti-FUT1 / HSC Antibody - LS-C310412 from LifeSpan Bioscience
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Anti-FUT1 / HSC Antibody (aa1-316) - LS-C311471 from LifeSpan Bioscience
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Anti-FUT1 / HSC Antibody - LS-C308036 from LifeSpan Bioscience
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Blood group H inhibitor Antibody - NBP1-57016 from Novus Biologicals
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Rabbit Anti-FUT1 Polyclonal Antibody - bs-7636R from Bioss
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Anti-FUT1 antibody produced in rabbit - SAB2105566 from Sigma-Aldrich
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Anti-FUT1 antibody produced in rabbit - SAB1410462 from Sigma-Aldrich
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Anti-FUT1 antibody produced in mouse - SAB1405832 from Sigma-Aldrich
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FUT1 Antibody (OAAD00001) - OAAD00001 from Aviva Systems Biology
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H Antibody (OAMA00514) - OAMA00514 from Aviva Systems Biology
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FUT1 antibody - middle region (ARP44222_P050) - ARP44222_P050 from Aviva Systems Biology
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FUT1 Antibody - middle region (OAAB03584) - OAAB03584 from Aviva Systems Biology
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FUT1-Antibody-Center - AP6573c from Abgent, a WuXi AppTec company
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Fut1-mouse-Antibody-internal-region - AF3567a from Abgent, a WuXi AppTec company
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ADAM12 antibody, N-term - GTX89596 from GeneTex
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Her3 / ErbB3 antibody [RTJ2] - GTX19389 from GeneTex
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FUT1 antibody [N1C3] - GTX100800 from GeneTex
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FUT1 antibody, Internal - GTX81834 from GeneTex
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HSP90 antibody [SJ-90] - GTX11156 from GeneTex
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